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Protein Complex Movement May Regulate Cell Division, Impacting Disease Research

Scientists at Umeå University in Sweden have found that the movement of a unique protein complex known as the Mediator along DNA genes may affect the process of cell division.

6 May 2024

Enhancing Drug Discovery Through Automated Protein Labeling

Exact protein observation in cells is crucial for many scientific fields, but it has proven to be a difficult technical task, particularly in living cells where each protein needs to have its fluorescent label applied separately.

22 Apr 2024

Researchers Uncover the FACT-ETS-1 Antiviral Response Pathway

By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide variety of viruses.

4 Apr 2024

Study may Provide a Roadmap for Addressing Cytokine Storms in Severe COVID-19

A recent USC study provides new information about why SARS-CoV-2, the virus behind the COVID-19 pandemic, may elicit mild symptoms at first but then, for a subset of patients, turn potentially fatal a week or so after infection.

1 Apr 2024

Bioinformatics Tool Recognizes Chromosome Changes in Cancer Cells

A group from IRB Barcelona and the University of Barcelona has created a novel bioinformatics instrument to recognize the chromosomal changes characteristic of cancerous cells.

22 Mar 2024

Study Identifies Protein Key to Preserving Neuronal Identity

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

13 Mar 2024

The Secrets of Toxic Algal Blooms: A Deep Dive into Prorocentrum cordatum's Cell Biology

Professor Dr Ralf Rabus of the University of Oldenburg has carried out the first comprehensive analyses of the peculiar cell biology of Prorocentrum cordatum, a globally distributed species of the dinoflagellates group.

6 Mar 2024

3D Visualizations of the Copying Machinery Found in Chloroplasts

Plants have to carry out photosynthesis and ultimately synthesize oxygen and chemical energy with the assistance of sunlight to support life on Earth.

4 Mar 2024

Researchers Identify Genes Linked to Genomic Instability and DNA Damage

More than one hundred key genes linked to DNA damage have been uncovered through systematic screening of nearly 1,000 genetically modified mouse lines, in a new study published today (14 February) in Nature.

16 Feb 2024

Unraveling Lenacapavir's Impact on the HIV Life Cycle

A new anti-retroviral medication for the treatment of human immunodeficiency virus (HIV) infections was licensed by the US Food and Drug Administration and the European Union just over a year ago.

14 Feb 2024

New Research Sheds Light on Divergent Roles of Paralogous RNA Helicases

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

9 Feb 2024

Scientists Reveal HIV's Secret Weapon for Invading Cell Nucleus

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

New Technique Reveals Order and Flow in the Cell's Control Center

Though its material characteristics still baffle scientists, the cell nucleus is thought to be the center of control for essential cellular functions

22 Jan 2024

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

22 Dec 2023

How 3D DNA Architecture Shapes Cell Fate in Early Embryos

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time.

21 Dec 2023

Non-Invasive Early Cancer Detection Using Chromatin Signatures in Mononuclear Blood Cells

Blood cells reveal tumors in the body. Researchers at the Paul Scherrer Institute achieve an advance with the development of a test for early diagnosis of cancer.

18 Dec 2023

Unraveling the Complexities of Gene Regulation with MAbID

A novel technique named MAbID, developed by researchers led by Jop Kind, has been introduced to concurrently investigate various mechanisms of gene regulation, crucial for both development and disease processes.

5 Dec 2023

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

5 Dec 2023

New Model Reveals How Cells Maintain Epigenetic Memory During Cell Division

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

17 Nov 2023

Study Discovers Fanzors in Eukaryotic Organisms

Snails, algae, and amoebas all have programmable DNA-cutting enzymes called Fanzors, and a recent study from Massachusetts Institute of Technology’s (MIT) McGovern Institute for Brain Research has found hundreds of them.

16 Oct 2023