Gastrointestinal Tract News and Research

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Role of Candidalysin in Gut Microbiome Dynamics

The fungus Candida albicans commonly inhabits the human gastrointestinal tract. This versatile species can switch between existing as single-celled yeast and multicellular hyphae to adjust to its surroundings.

22 Mar 2024

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

18 Mar 2024

EPFL Scientists Develop Platform for Orally Available Cyclic Peptide Drugs

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

29 Dec 2023

Gut Microbes Key to Alleviating Canine Inflammatory Bowel Disease

Researchers at Oregon State University – Cascades have led a study that suggests gut microbes discovered in wild wolves could hold the solution to relieving a prevalent gastrointestinal ailment in domestic dogs.

3 Oct 2023

Study Highlights Critical Development Window During Which Racial Differences in Gut Microbiome Emerge

Early social and environmental exposures can have large and lasting effects on child development and adult health.

18 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Mast Cells May Help Humans Avoid Harmful Antigens

Mast cells, which are part of the immune system, are still a puzzle. Mast cells function as a sensor that signifies the animals to avert antigens, including harmful allergens, and thus safeguard themselves from health-threatening inflammatory reactions, according to researchers at the German Cancer Research Center (DKFZ). The research was published in the journal Nature.

13 Jul 2023

Extraoral Bitter Taste Receptors Serve as Endogenous Sensors for Bile Acids

Taste receptors for bitter substances are not only observed on the tongue but also on cells outside of the oral cavity.

5 Jul 2023

Fructose is Needed for Enhanced Egg Production in Fruit Flies, Study Reveals

To many people, the sugars we eat may seem like a luxury that can do more harm than good. But now, researchers from Japan have discovered that in insects, dietary sugars play a key role in reproduction.

25 May 2023

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. I

24 May 2023

Understanding How Diet may Influence the Gut Microbiota Structure

We know that eating a healthy diet affects body weight, cholesterol levels, and heart health. A new study from the University of Illinois focuses on another component: the role of diet in supporting a healthy gastrointestinal microbiota.

5 May 2023

Diet Plays a Bigger Role in Shaping Intestinal Microbiota Composition Than Defensins

Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.

4 May 2023

40% of Supermarket Meat Samples Contain Multidrug-Resistant Bacteria

Multidrug-resistant E. coli were found in 40% of supermarket meat samples tested in a Spanish study.

17 Apr 2023

Exceptional Number of Unknown Viruses Found in the Infants' Feces

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

12 Apr 2023

Promoting Gut Health in Mice with Broccoli Consumption

It is well known that broccoli is good for human health. For instance, studies have indicated that increasing the intake of cruciferous vegetables lowers the risk of type 2 diabetes and cancer.

7 Apr 2023

Microbial Composition of the Gut may Affect a Child's Susceptibility to ADHD

New research published in the Journal of Child Psychology and Psychiatry suggests that the microbial composition of the gut may affect a child's susceptibility to attention-deficit/hyperactivity disorder (ADHD).

6 Apr 2023

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut.

27 Mar 2023

New compound may offer a way to prevent serious C. diff infections

Each year, about 500,000 people in the U.S. deal with gastrointestinal infections from Clostridioides difficile (C. diff), and more than 20,000 die from these infections.

27 Mar 2023

New model, C. elegans, helps pursue research on Parkinson's disease

A tiny worm called the C. elegans is enabling scientists to explore the emerging theory that Parkinson's disease starts in the gut.

1 Mar 2023

Adults struggling with chronic constipation benefit from a vibrating capsule

A vibrating capsule designed to stir the colon to action appears to double the ability for adults struggling with debilitating chronic constipation to defecate more normally and without drugs, researchers report.

22 Feb 2023