Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

New Virus Offers Hope for Amphibians Ravaged by Fungus

A fungus devastating frogs and toads on nearly every continent may have an Achilles heel. Scientists have discovered a virus that infects the fungus, and that could be engineered to save the amphibians.

4 Apr 2024

Tandem Repeat Expansions Linked to Cardiomyopathy Risk, Reveals Study

In the first study to use whole genome sequencing to examine tandem repeat expansions in heart conditions, scientists at The Hospital for Sick Children (SickKids) have laid the groundwork for early detection of and future precision therapies for cardiomyopathy.

28 Feb 2024

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Epigenetic Regulator MOF Plays Critical Role in Mitochondrial Function

The intricate control of cellular metabolism relies on the coordinated and harmonious interplay between the nucleus and mitochondria.

10 Oct 2023

Scientists Discover New Pathway for Biosynthesis of Cardenolides in Plants

Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants.

19 Sep 2023

Study Identifies 39 Genetic Mutations Associated With Heart Failure

In a new study co-led by investigators at the United States Department of Veterans Affairs and Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, a global team of scientists conducted one of the largest genetic association studies on heart failure to date.

25 Aug 2023

New Process by Which Enzymes Help Prevent Heart Damage in Chemotherapy Patients Identified

Researchers at the University of Illinois Chicago have identified a process by which enzymes can help prevent heart damage in chemotherapy patients.

21 Jul 2023

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Proteins that work like air traffic controllers, controlling the flow of signals in and out of human cells, have been examined in unparalleled detail for the first time using modern microscope techniques.

5 May 2023

UCF Scientists Develop a Digital Topographical Map of the Cardiac Sympathetic Neural Network

A team of UCF College of Medicine researchers has created a digital topographical map of the cardiac sympathetic neural network, the region that controls the body's heart rate and its "fight-or-flight" response.

18 Apr 2023

Study helps understand at the cellular level how physical activity contributes to fitness during aging

Regular exercise can guarantee quality of life and longevity, specialists agree. However, exactly how exercise influences the functioning of muscle cells is poorly understood.

30 Mar 2023

High blood caffeine levels lower body fat and the long-term risks of type 2 diabetes, study finds

A high blood caffeine level might curb the amount of body fat a person carries and their risk of type 2 diabetes, suggests research published in the open access journal BMJ Medicine.

16 Mar 2023

Researchers provide an entirely new perspective on tissue oxygenation

Cardiovascular medicine, hematology and pulmonary medicine may soon have the first-ever therapies to correct poor tissue oxygenation, a key driver of disease in millions, including peripheral artery disease, sickle cell disease, heart failure, stroke, emphysema and many others.

2 Mar 2023

Cell therapy trial promises long-term improvement for patients with chronic heart failure

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

28 Feb 2023

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

31 Jan 2023

Role of clonal hematopoiesis as a broad driver of atherosclerosis

A group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), collaborating with institutions in the USA, has shown that acquired mutations in the gene encoding the protein p53 contribute to the onset of atherosclerotic cardiovascular disease.

18 Jan 2023

Molecular mechanisms behind mitochondrial dysfunction in chronic heart failure

Chronic heart failure induces dysfunction in the cell’s powerhouses, which is caused in part by an excess of an essential intermediate compound in energy production. Compensating for this by supplementing the diet could be a potential technique for treating heart failure.

26 Oct 2022

COVID-19 spike protein caused severe heart damage, new research shows

Heart damage is prevalent in COVID-19 patients, leading many to doubt how the virus impacts the heart.

28 Jul 2022

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

University of Cape Town (UCT) researchers have used cryo-electron microscopy to identify the first complete structures of the human angiotensin-converting enzyme (ACE) (cryo-EM). A protein that controls blood pressure, ACE, is essential for maintaining good heart health.

14 Jul 2022

Cellular therapy leads to meaningful functional improvements in DMD patients

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

From The University of California, Davis 14 Mar 2022

Why is it Important to have Diverse Genomics Data in Science?

In this interview, we speak to Dr. Santiago Miriuka, CEO of MultiplAI Health, about the importance of having diverse genomics data in research.

From MultiplAI Health 17 Feb 2022