Kidney News and Research

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Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

4 May 2023

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Ribonucleic acids (RNAs) are single-stranded molecules that are found in all living organisms’ cells. As “transcripts” of human genes, mRNAs, for instance, play a role in the translation of genetic information by bearing the instructions for the production of a protein in their own sequence.

26 Apr 2023

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

The mathematical and biological mechanisms underlying the rugged structures at cell boundaries present in tissues like the kidneys and nasal glands have been discovered.

26 Apr 2023

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

A breakthrough in gene variants of an inflammation “brake” brings researchers one step closer to developing personalized treatments for those at risk of kidney disease and kidney failure.

26 Apr 2023

Antibacterial Biologic Agent Effective Against Staphylococcus Aureus Infections in Early Tests

Researchers at NYU Grossman School of Medicine and Janssen Biotech, Inc. have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.

25 Apr 2023

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

At St Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard, researchers have shown how prime editing could help correct the mutation that results in sickle cell disease in a possibly curative method.

18 Apr 2023

Study Represents a Paradigm Shift in Renal Physiology/Mammalian Salt Handling

A new study led by Marshall University researchers focuses on a novel mechanism of the body's regulation of salt balance.

3 Apr 2023

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

3 Apr 2023

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.

31 Mar 2023

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

31 Mar 2023

Previously unknown telomere and cancer connection to the immune system revealed

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

31 Mar 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

Generating functional patient-specific thymic organoids from human pluripotent stem cells

Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells, researchers report March 23rd in the journal Stem Cell Reports.

24 Mar 2023

BetaLife and A*STAR team up to accelerate the development of new cell-based therapy for diabetes

Up-and-coming local biotech startup BetaLife Pte Ltd ("BetaLife") is collaborating with the Agency for Science, Technology and Research (A*STAR) to accelerate the development of next generation cell-based therapy for diabetes.

22 Mar 2023

Keck Medicine of USC launches clinical trial investigating innovative procedure to control Type 2 diabetes

More than 37 million Americans have diabetes, and approximately 90-95% have Type 2 diabetes.

21 Mar 2023

Highlighting a potential sex‐specific precision immunotherapy strategy

Immunotherapy is an effective form of treatment for various types of cancer. However, its effect on pancreatic cancer is restricted and varies between men and women. Karolinska Institutet scientists have observed a possible explanation for this gender difference.

17 Mar 2023

Artificial pancreas helps improve blood sugar control in children with type 1 diabetes

An artificial pancreas originally developed at the University of Virginia Center for Diabetes Technology improves blood sugar control in children ages 2 to 6 with type 1 diabetes, according to a new study.

16 Mar 2023

Experts receive funding to analyze individualized hemodialysis as a dynamic treatment

The Patient-Centered Outcomes Research Institute (PCORI) recently awarded researchers at Wake Forest University School of Medicine $10.2 million to study the effectiveness of an individualized model of hemodialysis, a procedure in which the blood is cleaned by a dialysis machine. The project is a collaboration between the School of Medicine, the Renal Research Institute and other health care systems across the country.

10 Mar 2023

Study shows link between a mitochondrial metabolite and activation of inflammatory response

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

9 Mar 2023

Kidney News and Research

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

Antibacterial Biologic Agent Effective Against Staphylococcus Aureus Infections in Early Tests

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

Study Represents a Paradigm Shift in Renal Physiology/Mammalian Salt Handling

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

Previously unknown telomere and cancer connection to the immune system revealed

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Generating functional patient-specific thymic organoids from human pluripotent stem cells

BetaLife and A*STAR team up to accelerate the development of new cell-based therapy for diabetes

Keck Medicine of USC launches clinical trial investigating innovative procedure to control Type 2 diabetes

Highlighting a potential sex‐specific precision immunotherapy strategy

Artificial pancreas helps improve blood sugar control in children with type 1 diabetes

Experts receive funding to analyze individualized hemodialysis as a dynamic treatment

Study shows link between a mitochondrial metabolite and activation of inflammatory response

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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