Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

SYCE2 Gene Variant Disrupts Alignment of Chromosomes, Potentially Leading to Pregnancy Loss

Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled "Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effects on recombination".

30 Jan 2024

Scientists Harness Cellular Scaffolding for New Bio-Inspired Technologies

Princeton researchers have learned to harness the gossamer scaffolding that maintains the structure of living cells and used it to develop a nanotechnology platform.

27 Jan 2024

Phage Proteins Tame CRISPR-Cas3, Paving Way for Precise Gene Therapy

Through the use of CRISPR, an immune system that bacteria use to defend themselves against viruses, researchers have been able to alter genetic information within cells.

22 Jan 2024

Study Uncovers Chromatin Modifier-Centered Pathway for Grain Size Regulation in Rice

Chromatin is the complex of DNA and proteins that makes up the genetic material in the nucleus of eukaryotic cells.

18 Jan 2024

Commercializing Innovation in a Life Sciences Ecosystem

In this interview, Glennis Mehra, the Director of BioLabs at NYU Langone, shares her journey through the life sciences industry and delves into the role of BioLabs as an incubator for early-stage life science companies.

17 Jan 2024

Epigenetic Key Unlocks Treatment Path for Endocrine-Resistant Breast Cancer

Endocrine resistance – a major cause of breast cancer deaths – can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered.

10 Jan 2024

New Method Designs Proteins With Complex Shapes

A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin.

5 Jan 2024

Unveiling Cytonemes, the Secret Messengers of the Nervous System

Researchers at St. Jude Children’s Research Hospital captured images of cytonemes, which are cellular projections that are involved in long-distance signal transmission during development.

3 Jan 2024

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

26 Dec 2023

Deciphering the Structure and Function of PLD3 in Cellular Waste Disposal

If we don't take out the trash regularly, our homes become unpleasant and even a danger to our health.

21 Dec 2023

Sirtuin 6 Boosts DNA Repair in Aging Cartilage Cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes."

20 Dec 2023

New Cell Model Paves Way for Faster Treatments for Neuromuscular Diseases

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

20 Dec 2023

New AI-Generated Proteins Could Revolutionize Medicine and Beyond

A new study Dec. 18 in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring.

19 Dec 2023

Omicron's Cellular Senescence May Explain Cytokine Storms and Long-COVID

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence."

18 Dec 2023

Free AI Drug Discovery Course Surpasses 2,500 Users

An online course on Disease Modeling and Target Discovery launched 7 months ago by clinical stage generative artificial intelligence (AI)-driven biotechnology company Insilico Medicine has surpassed 2,500 users.

12 Dec 2023

Unveiling the Role of the Cerebellum in Human Cognitive Evolution

The development of advanced cognitive functions in humans has primarily been associated with the growth of the neocortex, a brain region responsible for conscious thought, movement, and sensory perception.

30 Nov 2023

Scientists Discover New Class of Molecular Glue Degraders for Cancer Therapy

Cells contain molecular machinery that targets and disposes of unwanted proteins to maintain homeostasis.

17 Nov 2023

Quantum Biology and AI Improve CRISPR Cas9 Efficiency in Microbes

Scientists at Oak Ridge National Laboratory used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

10 Nov 2023

SPT5 Identified as a Potential Target Protein for Treatment of MYC-Dependent Cancers

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins - with clear consequences for the tumor.

8 Nov 2023

Genetics can Improve the Diagnostic Value of Cyanobacterial Biomarkers

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

30 Oct 2023