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DNA Aptamer Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

12 Oct 2023

How RNA Regulates Gene Silencing Could Pave Way for Novel Cancer Therapies

Deep inside our cells-;each one complete with an identical set of genes-;a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

27 Sep 2023

Retrieving RNA from an Extinct Species

New research demonstrates the isolation and sequencing of RNA molecules from a Tasmanian tiger specimen kept at room temperature in a museum collection over a century ago.

20 Sep 2023

Fruit Fly Study Reveals New Insights into Exercise and Cold Tolerance

As the northern hemisphere experiences shorter and colder days, individuals who prefer morning workouts may encounter increased difficulty in getting up and running.

19 Sep 2023

Scientists Discover New Pathway for Biosynthesis of Cardenolides in Plants

Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants.

19 Sep 2023

Musashi-2 Protein Plays Key Role in Skeletal Muscle Mass and Metabolism

Investigators at Tokyo Metropolitan University have demonstrated the pivotal role of the Musashi-2 (Msi2) protein in governing mass and metabolic functions within skeletal muscle.

11 Sep 2023

Red Blood Cells May Hold the Key to Preventing Heart Diseases

An innovative KI study published in the Journal of Clinical Investigations found that red blood cells exposed to oxygen deficiency safeguard against myocardial infarction. The research also showed that a nitrate-rich vegetable diet boosts the protective effect.

4 Sep 2023

UC Davis Researchers Develop Tool to Predict Which Forests can Survive Future Drought

How long can trees tolerate drought before the forest dies? Researchers from UC Davis can now predict which forests could survive despite future drought.

30 Aug 2023

Gene Therapy Shows Promise for Muscular Dystrophy Patients

Researchers at Cincinnati Children’s Hospital reveal how damage to the cell’s energy factory causes muscle wasting. Closing a pore in the mitochondrial membrane in gene-edited mice prevents disease progression.

28 Aug 2023

Researchers Gain Insights Into Brain's Voluntary Mechanisms

Picture this scenario: You and a friend are walking around your neighborhood when you stop at a crosswalk. As you wait, the noises of the world and your internal thoughts all vie for your attention. Suddenly, you see a motorist nearly hit a bicyclist.

24 Aug 2023

Protein Analysis of Ancient Cauldrons Reveals Diet of Caucasus People

Archaeologists have long been drawing conclusions about how ancient tools were used by the people who crafted them based on written records and context clues.

21 Aug 2023

Animal Protein More Metabolically Responsive Than Plant Protein in Young and Older Adults, Study Finds

Protein from two ounce-equivalents (oz-eq) of animal-based protein foods provides greater essential amino acids (EAA) bioavailability than an equal two oz-eq of plant-based protein foods, according to scientists at Purdue University.

16 Aug 2023

Revealing a Novel Signaling Pathway Fostering Aging-Related Chronic Metabolic Disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

4 Aug 2023

Potential Strategies for Slowing Cognitive Deterioration in Age-Associated Neurodegenerative Conditions

As we age, our bodies undergo various changes that can impact our overall health and make us more susceptible to diseases.

3 Aug 2023

New Insights Into Lactate Transporters and Their Therapeutic Potential

Researchers from the Giulio Superti-Furga Lab at CeMM, the Austrian Academy of Sciences’ Research Center for Molecular Medicine, have developed a new technique for identifying specific inhibitors of a lactate transporter linked to cancer and other diseases.

31 Jul 2023

Bioengineers Harness 3D Printing to Create Functional Heart Ventricle

Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures.

28 Jul 2023

A Common Diabetes Drug Helps Prevent Muscle Atrophy and Muscular Fibrosis

You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis-;which can help the elderly bounce back faster from injury or illness.

26 Jul 2023

LION™-Formulated repRNA in Next-Gen repRNA Vaccine Platform Appears Promising

The creation of new vaccination technologies continues to be at the forefront of scientific inquiry as the globe fights numerous infectious illnesses. Recent research on illnesses like COVID-19 has shown promise for mRNA-based vaccines and their use of lipid nanoparticles (LNPs) for delivery.

25 Jul 2023

T Cells Play a Dual Role in Wasting During Infection

Even though infections can be presented with several different symptoms, one common symptom is known to be the loss of fat and muscle, a process known as wasting.

25 Jul 2023

New Study Highlights Genetic Variations for a Precision Medicine Approach

There are genetic variations among children with a rare neurodevelopmental disease, according to a new study headed by the Seaver Autism Center for Study and Treatment at Mount Sinai. This discovery could set the path for a precision medicine approach to treating these children.

18 Jul 2023