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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Small RNA-Binding Protein Promotes Prime Editing Efficiency

Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.

23 Apr 2024

Revealing the Genetic Mechanisms Driving SARS-CoV-2 Variants

The SARS-CoV-2 virus, responsible for COVID-19, exhibits a troubling tendency to produce variants frequently.

23 Apr 2024

Researchers Highlight Crucial Contributions of Astrocytes to Mental Health

The health and function of the brain depend on astrocytes, which are essential cells in the central nervous system. According to recent research, they affect behaviors and higher cognitive functions by controlling local neuronal activity.

22 Apr 2024

Protein TRBP's Regulatory Role in Immune Response to Viral Infections Uncovered

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

22 Apr 2024

KIT Researchers Uncover New Cell Type Responsible for Vascular Growth

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

Placenta's Role in Gestational Diabetes Revealed

A recent study led by the Harvard Pilgrim Health Care Institute has discovered that a deficiency in placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low circulating levels of IGFBP1 are linked to insulin resistance during pregnancy, indicating a potential risk factor for the onset of gestational diabetes.

17 Apr 2024

What Makes Certain Mushrooms 'Magic'?

In a recent study published in the journal Nature Communications, an international research team from various Universities including Hans Knöll Institute investigated the biosynthesis of psilocybin, the primary component of hallucinogenic mushrooms.

17 Apr 2024

Breakthrough RNA-Based Vaccine Strategy Offers Universal Protection

Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.

16 Apr 2024

Nasal Cells in Children Shield Against Severe COVID-19

Children usually have milder COVID-19 symptoms; this could be due to differences in how elderly and young people's nasal cells react to the SARS-CoV-2 virus.

16 Apr 2024

Unlocking the Potential of CRISPR/Cas13 for Antiviral Therapy

RNA viruses like SARS-CoV-2 demand new solutions. CRISPR/Cas13 tools work well against these viruses in the cell's nucleus, but not in the cytoplasm, where many replicate.

15 Apr 2024

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

13 Apr 2024

Meta-Analysis of ABA-Related Stress Responses Reveals Novel Gene Targets in Thale Cress

Plants can be temperamental. Even weeds along the side of highways or pushing their way up in the cracks of concrete sidewalks can get stressed out by dehydration, cold, excess salt and more.

13 Apr 2024

Different Chromosomes Found to Have Separate End-Specific Telomere-Length Distributions

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Bio-Techne Surpasses 10,000 Peer-Reviewed Publications Citing RNAscope Technology

Bio-Techne Corporation today announced that Advanced Cell Diagnostics (ACD), part of Bio-Techne's Spatial Biology Division, has surpassed 10,000 peer-reviewed publications referencing the use and application of RNAscope™ ISH technology.

From Bio-Techne 10 Apr 2024

Precision Combination Therapy Better Controls High-Risk Subtypes of B-ALL in Mouse Models

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

9 Apr 2024

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

9 Apr 2024

Nature's 'Molecular Kitchen': Heat Flows and the Origin of Life's Ingredients

Life is complicated. What is true for our everyday existence also holds for the many complex processes that take place inside cells

5 Apr 2024

RNA Modification Offers Hope for Treating Neurological Diseases

The research team led by Yongchao C. Ma, Ph.D., at the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, uncovered a fundamental biological mechanism that holds promise for the development of novel treatments for neurological disorders like spinal muscular atrophy (SMA) and autism, as well as various types of cancer.

5 Apr 2024

RNA Molecules Govern Battle Between Cholera Bacteria and Phages

Viruses need hosts. Whether it's measles, the flu or coronavirus, viral pathogens cannot multiply or infect other organisms without the assistance of their hosts' cellular infrastructure.

5 Apr 2024

New Virus Offers Hope for Amphibians Ravaged by Fungus

A fungus devastating frogs and toads on nearly every continent may have an Achilles heel. Scientists have discovered a virus that infects the fungus, and that could be engineered to save the amphibians.

4 Apr 2024