Transcriptomics News and Research

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Epigenomic Analysis Reveals Potential Treatment Avenues for ALS

For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.

3 May 2024

Mapping Gene Signatures Unveils How Lewy Bodies Impact Brain Cells

A new study by scientists at Van Andel Institute provides an initial glimpse into the intricate molecular changes taking place in brain cells with Lewy bodies, crucial pathological markers of Parkinson’s disease and certain dementias.

17 Apr 2024

Cellular Atlas of the Human Ovary Offers Hope for Restoring Hormone Production and Fertility

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

9 Apr 2024

Unveiling the Hidden Lives of Microbes Deep Underground

A group of scientists working at Bigelow Laboratory for Ocean Sciences have created a novel technique that connects the genetics and functionality of individual microbes that are oxygen-free and exist far below the surface of the Earth.

3 Apr 2024

Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.

20 Mar 2024

The Evolution of Plant Cell Analysis with RevGel-seq Technique

Plant cell analysis has been completely transformed by recent advances in single-cell RNA sequencing (scRNA), such as the recently created “RevGel-seq” technique.

13 Mar 2024

ReSisTrace: Unveiling Pre-Existing Treatment Resistance in Cancer Cells

In many cancers, such as ovarian cancer, each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment.

14 Feb 2024

Newly Found Memory B Cell Remembers Allergies

A new cell that remembers allergies has been discovered by researchers from McMaster University and the Danish pharmaceutical company ALK-Abello A/S.

8 Feb 2024

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Bio-Techne Corporation (NASDAQ: TECH) today announced that its spatial biology brands, Lunaphore and Advanced Cell Diagnostics (ACD), will launch the first fully automated spatial multiomics workflow with same-section hyperplex detection of RNA and protein biomarkers.

From Bio-Techne 25 Jan 2024

High-Resolution Map Exposes Cellular Pathways to Fertility

An interdisciplinary team mapped the gene expression that takes place in mice during follicle maturation and ovulation using a state-of-the-art method of RNA tagging.

24 Jan 2024

Crape Myrtle Genome Unveiled: Unlocking Secrets of Beauty and Evolution

Crape myrtle (Lagerstroemia indica), a widely cherished ornamental plant, boasts a rich history, originating in Southeast Asia to Oceania and flourishing in cultivation centers like China for over 1600 years.

24 Jan 2024

SPACEL: A Powerful AI Toolkit for Unveiling the 3D Secrets of Tissues

Spatial transcriptomics (ST) technologies are applied in biology and medical research for its ability to detect the spatial distribution of transcriptome in histological tissue slices.

3 Jan 2024

AI Tool Offers a Deep Dive Into Tissues, Boosting Cancer Detection and Treatment

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

3 Jan 2024

Deciphering the Tumor Microenvironment with Spatial Transcriptomics

Spatial transcriptomics (ST) has emerged as a crucial technique for mapping gene expression across tissue sections while preserving vital locational data, setting it apart from traditional methods like bulk or single-cell RNA sequencing.

30 Nov 2023

Yeast-Based Method Could Accelerate Discovery of Plant-Based Medicinal Compounds

Cornell researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes in a kratom tree.

19 Oct 2023

The Powerful Limb Regeneration Capabilities of Axolotl

Researchers from EPFL shed light on the axolotl’s unrivaled limb regeneration ability, contradicting long-held assumptions and providing fresh insights into possible mammalian limb restoration.

12 Oct 2023

Retrieving RNA from an Extinct Species

New research demonstrates the isolation and sequencing of RNA molecules from a Tasmanian tiger specimen kept at room temperature in a museum collection over a century ago.

20 Sep 2023

The Last Piece of Our Genome: Sequencing the Y Chromosome

A full sequence of the Y chromosome, a feat that has challenged scientists for years, has been accomplished for the first time. In this interview, we speak to Dylan Taylor about this impactful research and how it may shape our understanding of human genetics.

1 Sep 2023

New Gene Discovery Could Revolutionize Sex Determination in Green Algae

An international team of researchers led by Dr. James Umen at the Donald Danforth Plant Science Center has made a groundbreaking discovery in the world of developmental biology.

13 Jul 2023

Mapping Immune Microenvironments in Human Placenta

Until recently, scientific evidence on the ability of SARS-CoV-2, the virus that causes COVID, to replicate in the human placenta has been inconclusive.

10 Jul 2023