Histology & Microscopy

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UCL Scientists Visualize the Molecular 'Nano-Machinery' That Causes Cilia to Beat

The first image of the structures that power human cilia – the tiny, hairlike projections that line our airways – has been produced by a team involving UCL researchers and could lead to much-needed treatments for people with rare cilial diseases.

14 Jun 2023

Key Atomic Structures of the Actin Filament Revealed Through Cryo-EM

Actin filaments -; protein structures critical to living movement from single cells to animals -; have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ends.

9 Jun 2023

Identifying How a Particular Riboswitch Regulates its Synthesis

Researchers across the world are in search of ways to combat bacteria that could evade the present arsenal of antibiotics. This is done as a measure to avoid a global health crisis.

2 Jun 2023

Newly Identified Cellular Mechanism Enhances Photosynthesis in Marine Phytoplankton

Take a deep breath. Now take nine more. According to new research, the amount of oxygen in one of those 10 breaths was made possible thanks to a newly identified cellular mechanism that promotes photosynthesis in marine phytoplankton.

1 Jun 2023

Using High-Energy X-Rays to Image Biological Specimens Without Damage

A pollen grain showing the nanofoam within or a diatom with the individual geometric structures inside clearly visible: Using high-energy X-rays from the PETRA III synchrotron light source at DESY, a team led by CFEL scientists Saša Bajt and Henry Chapman has managed to image these structures without damaging them.

31 May 2023

New Algorithm to Improve the Understanding of Protein Movements

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

31 May 2023

High-Resolution, Stable Brain Stimulation by Ultraflexible Nanoelectrodes

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

31 May 2023

'Lost' Immune Cells Could be Partly Blamed for Impaired Vaccine Responses During Aging

Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.

23 May 2023

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

17 May 2023

Long-Ignored Antibiotic may Provide Much-Needed Protection Against Multi-Drug Resistant Bacteria

An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study publishing May 16th in the open access journal PLOS Biology by James Kirby of Harvard Medical School, US, and colleagues.

17 May 2023

AI Used to Create 3D Model of 'Postal Workers' in Human Cells

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

12 May 2023

Researchers Develop a System to Deliver Antioxidants to the Mitochondria

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

11 May 2023

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Proteins that work like air traffic controllers, controlling the flow of signals in and out of human cells, have been examined in unparalleled detail for the first time using modern microscope techniques.

5 May 2023

Deep Learning Model for Label-Free Identification of Different Cancer Cells

Cancer cells that initiate metastasis, or the spread of the disease from its primary location, are different from cancer cells that stay in the original tumor. Distinguishing metastasis-initiating cell types can determine the severity of cancer and help medical practitioners decide on a course of treatment.

3 May 2023

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

2 May 2023

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

28 Apr 2023

Some Promising Human Antibodies can Fight New Variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

27 Apr 2023

Research Deepens Our Understanding of Circadian Rhythm Regulation

New research from a multidisciplinary team helps to illuminate the mechanisms behind circadian rhythms, offering new hope for dealing with jet lag, insomnia and other sleep disorders.

27 Apr 2023

Researchers Develop 9CN-Rhodol-Based Activatable Raman Probes With High Sensitivity

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

26 Apr 2023

Capturing Viruses in a Lipid Trap

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

26 Apr 2023

Histology & Microscopy

UCL Scientists Visualize the Molecular 'Nano-Machinery' That Causes Cilia to Beat

Key Atomic Structures of the Actin Filament Revealed Through Cryo-EM

Identifying How a Particular Riboswitch Regulates its Synthesis

Newly Identified Cellular Mechanism Enhances Photosynthesis in Marine Phytoplankton

Using High-Energy X-Rays to Image Biological Specimens Without Damage

New Algorithm to Improve the Understanding of Protein Movements

High-Resolution, Stable Brain Stimulation by Ultraflexible Nanoelectrodes

'Lost' Immune Cells Could be Partly Blamed for Impaired Vaccine Responses During Aging

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

Long-Ignored Antibiotic may Provide Much-Needed Protection Against Multi-Drug Resistant Bacteria

AI Used to Create 3D Model of 'Postal Workers' in Human Cells

Researchers Develop a System to Deliver Antioxidants to the Mitochondria

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Deep Learning Model for Label-Free Identification of Different Cancer Cells

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Some Promising Human Antibodies can Fight New Variants of SARS-CoV-2

Research Deepens Our Understanding of Circadian Rhythm Regulation

Researchers Develop 9CN-Rhodol-Based Activatable Raman Probes With High Sensitivity

Capturing Viruses in a Lipid Trap

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

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