Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Investigating Enhancer Function in Pluripotent Stem Cells

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

30 Apr 2024

Unlocking Brown Fat's Potential: Study Reveals Key Protein in Obesity Regulation

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

30 Apr 2024

Mapping Small Molecule-Protein Interactions for Drug Development

For most human proteins, there are no small molecules known to bind them chemically (so called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines.

30 Apr 2024

Genetic Insights: Safflower Genome Assembly Unlocks Key Traits for Crop Improvement

A research team completes a high-quality chromosome-scale assembly of the 'Chuanhonghua 1' safflower genome.

30 Apr 2024

Study Reveals Molecular Assembly of One of the Most Common Anti-Phage Systems

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

29 Apr 2024

New Study Discovers Gene Associated with Epilepsy and Autism

A genetic mutation or variation in the SCN2A gene is known to cause infantile seizures, autism spectrum disorder, and intellectual disability, among other moderate-to-severe impairments in movement, communication, feeding, and vision.

29 Apr 2024

Genome Assemblies of Musa ornata and Musa velutina Unveil Insights Into Banana Biology

The genus Musa, encompassing approximately 70 herbaceous species, is predominantly found in the tropical and subtropical regions of Asia and Oceania.

26 Apr 2024

Barley Varieties Influence Soil Microbial Communities, Finds Study

Different types of barley recruit distinct communities of soil microbes to grow around their roots by releasing a custom mix of sugars and other compounds, according to a new study led by Jacob Malone of the John Innes Center, UK, publishing April 25th in the open-access journal PLOS Biology.

26 Apr 2024

Researchers Make Fundamental Discovery to Combat Fusarium Head Blight in Wheat

Fungal disease Fusarium head blight (FHB) is on the rise due to increasingly humid conditions induced by climate change during the wheat growing season, but a fundamental discovery by University of Adelaide researchers could help reduce its economic harm.

26 Apr 2024

PI3K Enzyme's Dual Accelerator and Brake Mechanisms Uncovered

A group of researchers have expanded conventional knowledge on a critical enzyme that controls cell migration. In a recent publication in the journal Nature Communications, they reported that phosphoinositide 3-kinase (PI3K) not only acts as an accelerator to prompt cell motility, but it also has a built-in brake mechanism that impedes migration.

25 Apr 2024

Study Unravels How Tumors Evade Immune Response by Targeting T Cells

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer.

25 Apr 2024

Sphingolipid Mystery Solved: S1P May Protect Against Coronary Artery Disease

Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.

25 Apr 2024

Hydrogel Therapy: A Novel Defense Against Viral Infections

Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop.

24 Apr 2024

Using State-of-the Art Imaging to Understand Lipid Dysfunction in Alzheimer's

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

24 Apr 2024

Unlocking the Secrets of Lipid Droplet Proteins in Arabidopsis Thaliana Leaves

Lipid droplets (LDs) serve as storage organelles found in plant leaves and seeds. While the functions of seed LD proteins in lipid metabolism are well understood, many leaf LD proteins remain unidentified.

24 Apr 2024

Small RNA-Binding Protein Promotes Prime Editing Efficiency

Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.

23 Apr 2024

First Comprehensive Map of Protein Movement in Yeast Cell Cycle Revealed

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle.

23 Apr 2024

Study Uncovers Cells' Surprising Strategy to Control Signaling Pathways

Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.

23 Apr 2024

Revealing the Genetic Mechanisms Driving SARS-CoV-2 Variants

The SARS-CoV-2 virus, responsible for COVID-19, exhibits a troubling tendency to produce variants frequently.

23 Apr 2024

Researchers Identify Link Between Mitochondrial Depletion and Protein Build-Up in Neurons

Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer's.

22 Apr 2024