Antigen News and Research

RSS

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

According to a new study, a novel T cell genetically engineered by scientists from The University of Arizona Health Sciences can target and attack pathogenic T cells that are responsible for causing Type 1 diabetes. These latest findings may result in new immunotherapy therapies.

7 Dec 2020

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial, Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting.

7 Dec 2020

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

A subcutaneous injection of the immune-boosting drug teclistamab was found to be safe and elicit responses in a majority of patients with relapsed or refractory multiple myeloma, according to findings from a multi-institutional phase I study being presented by Alfred L. Garfall, MD, an assistant professor of Medicine in the division of Hematology-Oncology in the Perelman School of Medicine at the University of Pennsylvania, at the annual American Society of Hematology & Exposition Meeting on Dec. 5 (abstract #180).

7 Dec 2020

Specific immune mechanism in COVID-19 patients triggers inflammatory process

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

3 Dec 2020

New method to improve preclinical evaluation of CAR-T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.

9 Nov 2020

Study shows memory T cells are formed earlier than previously thought

A person will acquire immunity to a specific disease when T cells develop into memory cells after making contact with pathogens.

4 Nov 2020

Study sheds new light on penicillin allergy

Scientists have reported the first strong evidence of the role of HLA-B, a crucial histocompatibility complex gene, in penicillin allergy.

27 Oct 2020

Research on broadly neutralizing antibodies may lead to universal flu vaccine

New research from an immunology team at the University of Chicago may shed light on the challenges of developing a universal flu vaccine that would provide long-lasting and broad protection against influenza viruses.

23 Oct 2020

Novel technique could propel personalized treatments for cancer

When it comes to defeating cancer, some immune cells are mightier than others. But even the best-trained eye and today's advanced scientific tools have trouble discerning the most powerful tumor-fighting cells from the rest.

23 Oct 2020

Genomic differences can help develop more personalized treatments for African American men

Prostate cancer is the most common type of cancer among American men after skin cancer, but the disease does not affect all races equally.

22 Oct 2020

Novel approach based on microfluidic technology to fight cancer

CAR-T biotherapeutics company Carina Biotech and researchers at the University of South Australia have developed a novel approach based on microfluidic technology to "purify" the immune cells of patients in the fight against cancer.

21 Oct 2020

Researchers assign immunological memory function to cytotoxic natural killer cells

A new study by researchers from the Medical University of Vienna could prove beneficial for the human immune system.

21 Oct 2020

SARS-CoV-2 may induce long-term autoimmune disorder due to self-glycan antibody production

A new study indicated that many of the unusual symptoms of SARS-CoV-2 infections may be due to induced autoimmune responses.

20 Oct 2020

Bioinformatics expert to design antibody-antigen interface to predict peptide sequences

Dmitri Klimov, Professor, Bioinformatics and Computational Biology, is creating a computational platform for designing an antibody-antigen interface based on DNA origami.

19 Oct 2020

Researchers identify drug that could overcome tumor resistance

Scientists have discovered that a drug that may make some melanoma tumors perceptible to the immune system, enabling them to be better targeted.

15 Oct 2020

Army researchers test alternative ways to measure COVID-19 antibody levels

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale. Their method holds promise for accurately identifying potential donors who have the best chance of helping infected patients through convalescent plasma therapy.

15 Oct 2020

Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body's natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy.

15 Oct 2020

Antigen News and Research

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

Specific immune mechanism in COVID-19 patients triggers inflammatory process

New method to improve preclinical evaluation of CAR-T cell therapies

Study shows memory T cells are formed earlier than previously thought

Study sheds new light on penicillin allergy

Research on broadly neutralizing antibodies may lead to universal flu vaccine

Novel technique could propel personalized treatments for cancer

Genomic differences can help develop more personalized treatments for African American men

Novel approach based on microfluidic technology to fight cancer

Researchers assign immunological memory function to cytotoxic natural killer cells

SARS-CoV-2 may induce long-term autoimmune disorder due to self-glycan antibody production

Bioinformatics expert to design antibody-antigen interface to predict peptide sequences

Researchers identify drug that could overcome tumor resistance

Army researchers test alternative ways to measure COVID-19 antibody levels

Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

New software helps analyze individual cells in virtual reality

Treatment using immune system T cells preserves vision of mice with retinoblastoma

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

Latest in Genomics