Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Research sheds light on T cell abnormality in critically ill COVID-19 patients

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients.

23 Nov 2020

Researchers discover new 'hidden' gene in SARS-CoV-2

Researchers have discovered a new "hidden" gene in SARS-CoV-2--the virus that causes COVID-19--that may have contributed to its unique biology and pandemic potential.

11 Nov 2020

Scientists identify potential targets against coronavirus

Scientists comprehensively studied the RNA genomic structure of the SARS-CoV-2 coronavirus.

11 Nov 2020

Toxins produced by tube-dwelling anemones have pharmacological potential, shows research

Researchers based in Brazil and the United States have completed the first-ever mapping exercise to profile the toxins produced by tube-dwelling anemones, or cerianthids, a family of marine animals belonging to the same phylum (Cnidaria) as sea anemones, jellyfish and corals.

30 Oct 2020

Scientists explain the role of transcription factors in genetic diseases

Transcription factor proteins can be described as the light switches of the human genome. These proteins bind to DNA and allow genes to turn “on” or “off.”

26 Oct 2020

Experimental vaccine shows promise for treating and preventing cancer in mice

An experimental vaccine, designed to enlist the body's own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice.

23 Oct 2020

Study: Early travel restrictions have significantly limited the spread of COVID-19 virus

The coronavirus, responsible for the COVID-19 pandemic, has one official name--SARS-CoV-2. But according to virologists, mutations lead to hundreds of genetically-distinct versions of the virus.

23 Oct 2020

Novel technique could propel personalized treatments for cancer

When it comes to defeating cancer, some immune cells are mightier than others. But even the best-trained eye and today's advanced scientific tools have trouble discerning the most powerful tumor-fighting cells from the rest.

23 Oct 2020

Cell nucleus may enable the cells to evade crowded environments

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free.

20 Oct 2020

Bioinformatics expert to design antibody-antigen interface to predict peptide sequences

Dmitri Klimov, Professor, Bioinformatics and Computational Biology, is creating a computational platform for designing an antibody-antigen interface based on DNA origami.

19 Oct 2020

CRISPR platform can accelerate potential treatment targets for SARS-CoV-2

Synthego has provided multiple CRISPR-based engineered cell lines to speed up the analysis of promising treatment targets for SARS-CoV-2.

19 Oct 2020

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

A large international consortium of almost 200 researchers from 14 leading institutions in six countries has studied three different coronaviruses - SARS-CoV-1, SARS-CoV-2, and MERS-CoV - with the aim of finding vulnerabilities shared by these three pathogens.

16 Oct 2020

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Scientists develop UK Crop Microbiome Cyrobank to facilitate sustainable yield improvement

Scientists from the UK's foremost agricultural research institutes have teamed up to create a new UK Crop Microbiome Cyrobank (UK-CMCB) to safeguard future research and facilitate the sustainable yield improvement of the UK's six major food crops including barley, oats, oil seed rape, potato, sugar beet and wheat.

12 Oct 2020