CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

UCI biologists discover how a gene variant protects against Alzheimer's disease

While the word "mutation" may conjure up alarming notions, a mutation in brain immune cells serves a positive role in protecting people against Alzheimer's disease.

15 Feb 2022

New methodology for 'compressing' extensive genetic data libraries to more manageable sizes

In image compression, a large file that could be cumbersome to store or share loses a small amount of visual information.

From Penn State University 15 Feb 2022

Genetic mutation introduced into human genome protects against Alzheimer’s disease, research says

Scientists were successful in editing the genome of human cells cultured in vitro to introduce a mutation offering protection from Alzheimer’s disease.

14 Feb 2022

Study creates a new wheat mutant with resistance to disease

Chinese scientists explained their use of genome editing to produce significant disease resistance without any growth problems in a study published online in Nature.

14 Feb 2022

Three proteins as potential new therapeutic targets in movement disorders

Three members of a family of proteins have been identified that are important to helping us fine tune the activity of brain chemicals which enable us to walk or stand at will, scientists report.

11 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

Scientists use CRISPRa to discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

4 Feb 2022

Research focuses on how short-term genetic memories can be inherited across generations

A gene-silencing tool could enable new opportunities for advancing basic biomedical research and drug development.

4 Feb 2022

CRISPR-Cas9 likely to cause unforeseen genetic variations, researchers warn

Commonly referred to as “genetic scissors,” the CRISPR-Cas9 opens up new avenues for disease treatment—however, treatments must be effective.

4 Feb 2022

An Interview with The Million Veteran Program (MVP)

In this interview, we speak to Dr. Sumitra Muralidhar, the Program Director for VA’s Million Veteran Program (MVP) about the program and its aims for veterans.

28 Jan 2022

Experts develop framework to assist in the demarcation between genetically modified and genome-edited organisms

To facilitate the demarcation between genetically modified organisms and genome-edited organisms, researchers at Hokkaido University have developed a framework that takes into account both scientific and socio-ethical considerations.

27 Jan 2022

Producing New Antibiotics Through Gene Editing

In this interview, we speak to Professor Jason Micklefield about his latest research that may be able to produce new antibiotics through gene-editing technologies.

From The University of Manchester 24 Jan 2022

Study findings greatly expand the ability to engineer long-range genome edits

Researchers discovered the potential of CRISPR, a tool used by bacteria to defend themselves against viral intruders, nearly a decade ago.

24 Jan 2022

High-speed cell sorter rapidly isolates and quantifies cells with complex cellular phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

Researchers discover a molecular mechanism linked with cholesterol movement

A team of researchers from the Universitat de Barcelona (UB) discovered a mechanism associated with the movement of cholesterol within cells.

From University of Barcelona 20 Jan 2022

Researchers identify new potential drug target that may block SARS-CoV-2 infection

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, which the novel coronavirus relies on to gain entry to its host's cells.

17 Jan 2022

CRISPR News and Research

Further Reading

UCI biologists discover how a gene variant protects against Alzheimer's disease

New methodology for 'compressing' extensive genetic data libraries to more manageable sizes

Genetic mutation introduced into human genome protects against Alzheimer’s disease, research says

Study creates a new wheat mutant with resistance to disease

Three proteins as potential new therapeutic targets in movement disorders

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

Scientists use CRISPRa to discover genes that play a role in immune cell biology

Research focuses on how short-term genetic memories can be inherited across generations

CRISPR-Cas9 likely to cause unforeseen genetic variations, researchers warn

An Interview with The Million Veteran Program (MVP)

Experts develop framework to assist in the demarcation between genetically modified and genome-edited organisms

Producing New Antibiotics Through Gene Editing

Study findings greatly expand the ability to engineer long-range genome edits

High-speed cell sorter rapidly isolates and quantifies cells with complex cellular phenotypes

Researchers discover a molecular mechanism linked with cholesterol movement

Researchers identify new potential drug target that may block SARS-CoV-2 infection

Scientists examine key mechanisms underlying genomic imprinting

Experts develop CRISPR-Cas9-mediated inheritance control in male mice

New gene determines whether ultraviolet iridescence shows up in butterfly wings

Experts develop Immuno-CRISPR assay to detect kidney transplant complications

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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