Cancer Treatment News and Research

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Epigenetic therapy can boost the ability of immune killer T-cells to destroy cancer cells

Developing “super soldiers” of particular white blood cells to promote an anti-tumor reaction has been demonstrated in a series of well-designed experiments.

23 Feb 2021

Gut microbiome alterations help melanoma patients to respond to immunotherapy

Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients' gut microbiome led them to respond to a type of treatment capable of providing long-term benefit.

17 Feb 2021

Scientists use new approach to avert drug resistance in glioblastomas

In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research.

11 Feb 2021

Researchers identify three genes regulating stemness of gastric tissue stem cells

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages.

9 Feb 2021

Yale scientists discover novel metabolic gatekeeper mechanism for leukemia

In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. The findings were published online today in the Proceedings of the National Academy of Sciences (PNAS).

2 Feb 2021

Research shows how breast cancer cells evade immune attacks

Scientists from Indiana University have discovered how breast cancer cells evade immune cells to survive.

28 Jan 2021

New method shows how pharmaceuticals induce cancer cell death

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.

20 Jan 2021

Researchers develop more effective personalized immunotherapy for cancer patients

New research from CU Cancer Center member Jing Hong Wang, MD, PhD, and recent University of Colorado Immunology program graduate Rachel Woolaver, PhD, may help researchers develop more effective personalized immunotherapy for cancer patients.

15 Jan 2021

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

Researchers report a potential cancer drug that targets mitochondrial function

A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read.

23 Dec 2020

Scientists find new way to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

18 Dec 2020

Research shows how microbubbles can be used to administer potent cancer drugs

New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumour using antibodies.

11 Dec 2020

Study reveals new target to make breast cancer more sensitive to immunotherapy

Although immunotherapy has been effective in treating different kinds of cancer, it is still unsuccessful when it comes to treating breast cancers.

11 Dec 2020

CTC dynamics related to overall survival in patients with metastatic breast cancer

Early circulating tumor cell dynamics were associated with overall survival in patients with metastatic breast cancer, according to a meta-analysis presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

10 Dec 2020

Study identifies a promising target for cancer treatment

If there is a positive aspect in cancer’s random biology, it is that the same characteristics that promote the growth of cancer cells usually present opportunities for destroying them.

2 Dec 2020

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 26 Nov 2020

Light-activated liposomes could help deliver CRISPR gene therapy

Light-activated liposomes could help to deliver CRISPR gene therapy - and the method could prove safer and more direct than current methods.

From The University of New South Wales (UNSW) 16 Nov 2020

Study shows how UCH37 enzyme regulates a cell’s waste management system

Researchers reported the discovery of a new enzyme, called UCH37, that controls the waste management system of a cell.

9 Nov 2020

New method to improve preclinical evaluation of CAR-T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.