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A missing link explains how class I molecules evolved from a class II-like origin Major Histocompatibility...

Which came first, MHC class I or MHC class II? For decades, it has been debated which of these two similar classes came first in evolution. Now, Keiichiro Hashimoto and his group at Fujita Health University, Japan, in collaboration with European research groups, have provided an answer to this question in a new article in PNAS.

14 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Study illustrates the concept of cool microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing movement of molecules that define its living state.

From The Max Planck Institute 14 Dec 2021

Each person has their own unique “fingerprint” of protein activity, says study

A group of international scientists recently generated a new approach to identify the proteins in human cells that are crucial for increasing sugar absorption after exercise.

14 Dec 2021

Experts identify ways to manipulate capsule-like DNA structures

Biophysicists from Japan recently identified ways to create and manipulate capsule-like DNA structures that can be employed in the development of artificial molecular systems.

14 Dec 2021

Study finding helps better comprehend necroptosis for treating diseases

A group of scientists from WEHI, for the first time, visualized a human cell death complex associated with autoimmune and inflammatory conditions.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 14 Dec 2021

Research reveals nutrient responses underpinning a potentially deadly, low-chlorophyll state in plants

Green is a color that is almost universally associated with plants-;for good reason. The green pigment chlorophyll is essential to plants' ability to generate food; but what happens if they don't have enough of it?

13 Dec 2021

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

13 Dec 2021

Infant's immune system may be better than the adult immune system

As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.

13 Dec 2021

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Why is Innovation Critical to Life Sciences Research?

In this interview, we speak to Kirstie Speck from Abcam about the importance of innovation within the life sciences and how its role will change over the next 10 years.

From Abcam 13 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

New mechanism makes cells under stress conditions stop their polarized growth

The Oxidative Stress and Cell Cycle Research Group at UPF has discovered a mechanism whereby cells under stress conditions stop their polarized growth. The study, published in the journal Cell Reports, was led by Elena Hidalgo and José Ayté, and the first author is Clàudia Salat-Canela.

13 Dec 2021

Research offers alternative cell option for organs-on-chips

Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don't exist or lack precision. In particular, these platforms can include the cells of a patient, thus resulting in patient-specific discovery.

13 Dec 2021

Study helps identify how immune system cells identify and eradicate tumors

In the last 10 years, immunotherapy has been used to save the lives of several cancer patients with lung cancer.

13 Dec 2021

Study shows how proteases help keep cells clean

Waste collectors collect and dispose of household waste. In cells, a similar process works to eliminate damaged and potentially hazardous proteins.

13 Dec 2021

Researchers regenerate cartilage using novel protein fragment

The existing methods for the regeneration of injured cartilage generate tissue that breaks down. This deterioration eventually leads to osteoarthritis—the commonly seen form of arthritis—affecting over 32.5 million grown-ups in the United States, as per the Centers for Disease Control and Prevention.

13 Dec 2021

Experts grow novel cell lines in a chemically defined medium

Researchers for the first time acquired stem cells from livestock that was grown under chemically defined conditions.

13 Dec 2021

Multiple exposure enhances antibody efficacy against COVID-19 variants

Antibodies produced by the immune system against the SARS-CoV-2 spike protein help pinpoint and avoid future infections.

13 Dec 2021

Cell News and Research

A missing link explains how class I molecules evolved from a class II-like origin Major Histocompatibility...

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Study illustrates the concept of cool microscopy

Each person has their own unique “fingerprint” of protein activity, says study

Experts identify ways to manipulate capsule-like DNA structures

Study finding helps better comprehend necroptosis for treating diseases

Research reveals nutrient responses underpinning a potentially deadly, low-chlorophyll state in plants

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

Infant's immune system may be better than the adult immune system

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Why is Innovation Critical to Life Sciences Research?

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

New mechanism makes cells under stress conditions stop their polarized growth

Research offers alternative cell option for organs-on-chips

Study helps identify how immune system cells identify and eradicate tumors

Study shows how proteases help keep cells clean

Researchers regenerate cartilage using novel protein fragment

Experts grow novel cell lines in a chemically defined medium

Multiple exposure enhances antibody efficacy against COVID-19 variants

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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