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Promoter Mutations and Their Association with Autism Risk

The RIKEN Center for Brain Science (CBS) employed genome mutation analysis to investigate the genetics of autism spectrum disorder (ASD) in people and their families. They found that the way a certain type of genetic mutation contributes to the illness differs from that of ordinary mutations.

29 Jan 2024

Study Sheds Light on a Decades-Long Mystery About How Retinal Photoreceptors Work

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical "vision" signals to the brain.

27 Jan 2024

Scientists Harness Cellular Scaffolding for New Bio-Inspired Technologies

Princeton researchers have learned to harness the gossamer scaffolding that maintains the structure of living cells and used it to develop a nanotechnology platform.

27 Jan 2024

Scientists Reveal HIV's Secret Weapon for Invading Cell Nucleus

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Bio-Techne Corporation (NASDAQ: TECH) today announced that its spatial biology brands, Lunaphore and Advanced Cell Diagnostics (ACD), will launch the first fully automated spatial multiomics workflow with same-section hyperplex detection of RNA and protein biomarkers.

From Bio-Techne 25 Jan 2024

A New Tool for Monitoring Neuronal Inhibition

By tracking when distinct subsets of brain cells activate, researchers have understood the complex activity patterns found in both human and animal brains for many years. Knowing how long those neurons stay active and when they turn off again is crucial to understanding the brain and its associated disorders.

24 Jan 2024

High-Resolution Map Exposes Cellular Pathways to Fertility

An interdisciplinary team mapped the gene expression that takes place in mice during follicle maturation and ovulation using a state-of-the-art method of RNA tagging.

24 Jan 2024

RNAs on the Cell Surface Regulate Neutrophil Recruitment

In recent times, scientists have encountered RNAs venturing beyond their traditional cellular domains. A study conducted at Yale provides valuable insights into their activities in these unconventional locations.

23 Jan 2024

Cholangiocarcinoma: New Organ-On-Chip Aims at Accelerating Research and Personalized Medicine

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it’s hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

23 Jan 2024

Boosting Central Memory T Cells with Targeted Protein Modulation

The Hackensack Meridian Center for Discovery and Innovation's (CDI) Xue Lab has made yet another advancement in the understanding of the immune system and its potential for disease-fighting modulation.

22 Jan 2024

New Technique Reveals Order and Flow in the Cell's Control Center

Though its material characteristics still baffle scientists, the cell nucleus is thought to be the center of control for essential cellular functions

22 Jan 2024

Phage Proteins Tame CRISPR-Cas3, Paving Way for Precise Gene Therapy

Through the use of CRISPR, an immune system that bacteria use to defend themselves against viruses, researchers have been able to alter genetic information within cells.

22 Jan 2024

CD4+ T Cells Revealed as Powerful Cancer Killers

Researchers have unveiled groundbreaking insights into CD4+ T cells, a kind of immune cell, demonstrating the potential for immunotherapies targeting melanoma, the most fatal kind of skin cancer.

22 Jan 2024

New Virus Targets Dormant Bacteria, Boosting Antibiotic Power

In nature, the majority of bacteria adhere to a minimalistic lifestyle. When faced with nutrient scarcity or stress, they initiate a controlled shutdown of their metabolism, entering a resting state.

22 Jan 2024

LJI Researchers Identify Late-Rising T Cells Crucial for CMV Control

Cytomegalovirus (CMV) is a pathogen that likes to lurk. Most adults already carry CMV, and they show no symptoms at all.

22 Jan 2024

McMaster Team Publishes Instruction Manual for Detecting Rare B Cells

Researchers with McMaster University have created the instruction manual that will help scientists across the globe find hard to detect B cells.

22 Jan 2024

Bacteria's Immune System Enhances the Effect of Antibiotics Against Cholera Pathogen

Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of Tübingen and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.

22 Jan 2024

DNA Repair Breakthrough: Scientists Reveal RecA's Precise Helix Navigation

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact double strands, and repairing the break based on the undamaged sequence.

22 Jan 2024

Stem Cell-Derived Brain Organoids on Ax-3 Mission Seek to Improve Modeling for Neurodegenerative Diseases

More than 5 million people worldwide are living with neurodegenerative disorders like Parkinson’s disease and primary progressive multiple sclerosis (PPMS).

19 Jan 2024

Golgi Organelle's Crucial Role in Stress Responses

For more than a century, scientists have been aware of a certain organelle found in plant cells. That organelle's crucial function in aging, however, has only recently been uncovered by UC Riverside scientists.

18 Jan 2024