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Machine learning approach to identify drugs that could be repurposed to fight Covid-19

When the Covid-19 pandemic struck in early 2020, doctors and researchers rushed to find effective treatments.

16 Feb 2021

Antioxidant in green tea may lead to new anti-cancer drugs

Green tea contains an antioxidant that may boost the concentrations of p53, called the “guardian of the genome,” for its potential to kill cancerous cells.

15 Feb 2021

Researchers use unique methods to map the mechanism behind cellular communication

A better understanding of cellular interactions is crucial to interpret several biological diseases and systems.

15 Feb 2021

Animal model yields important insights into T cell exhaustion

T lymphocytes, or T cells, are an important component of our immune system. They can recognize foreign proteins, so-called antigens, as peptide fragments - for instance, those derived from viruses or cancer cells.

15 Feb 2021

Researchers use mouse models to explain how cancer cells spread

Most tumors consist of a heterogenous mix of cells. Genetic mutations found only in some of these cells are known to aid with the spread and progression of cancer.

15 Feb 2021

Study reveals key process by which plants switch between different stress responses

To design effective strategies that protect significant agricultural crops from climate change, it is important to understand how plants react to stressful environmental conditions.

15 Feb 2021

Natural compounds in apples and other fruits may improve brain function

According to a new study, apples and other fruits contain natural substances that may help trigger the generation of new neurons in the brain.

15 Feb 2021

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant 'quiescent' state, enabling them to proliferate and generate new neurons.

12 Feb 2021

Researchers identify protein sequences that might be used by SARS-CoV-2 to infect cells

Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.

12 Feb 2021

Cell cycle of cancer cells can be disrupted using two commercially available inhibitors

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumor neuroblastoma can be disrupted at a key point causing tumor cell death.

12 Feb 2021

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease.

12 Feb 2021

New technique reveals natural structure of large enzyme complex

A new technique has revealed the natural structure of specifically massive and complex enzymes.

11 Feb 2021

N-terminal acetylation shields proteins from degradation and inhibits programmed cell death

A new study shows that proteins called IAPs, which can trigger programmed cell death, are inhibited by a specific chemical modification, and reveals that they play a wider role in protein quality control than previously assumed.

11 Feb 2021

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

11 Feb 2021

Research may help better understand the biochemistry underlying catalysis in cells

Investigators from the Institute of Scientific and Industrial Research at Osaka University, together with the Hiroshima Institute of Technology, have announced the discovery of a new protein that allows an organism to conduct an initial and essential step in converting amino acid residues on a crosslinked polypeptide into an enzyme cofactor.

From Osaka University 11 Feb 2021

Scientists discover how the 3D structure of eye-lens proteins is formed

The lens of the human eye gets its transparency and refractive power from the fact that certain proteins are densely packed in its cells.

11 Feb 2021

Scientists use new approach to avert drug resistance in glioblastomas

In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research.

11 Feb 2021

Cell News and Research

Machine learning approach to identify drugs that could be repurposed to fight Covid-19

Antioxidant in green tea may lead to new anti-cancer drugs

Researchers use unique methods to map the mechanism behind cellular communication

Animal model yields important insights into T cell exhaustion

Researchers use mouse models to explain how cancer cells spread

Study reveals key process by which plants switch between different stress responses

Natural compounds in apples and other fruits may improve brain function

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers identify protein sequences that might be used by SARS-CoV-2 to infect cells

Cell cycle of cancer cells can be disrupted using two commercially available inhibitors

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

New technique reveals natural structure of large enzyme complex

N-terminal acetylation shields proteins from degradation and inhibits programmed cell death

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Research may help better understand the biochemistry underlying catalysis in cells

Scientists discover how the 3D structure of eye-lens proteins is formed

Scientists use new approach to avert drug resistance in glioblastomas

Researchers identify tumor suppressor gene involved in stress response

Researchers program genome tool to target specific histone proteins

Unusual DNA folding leads to higher mutation rates

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Commercializing Innovation in a Life Sciences Ecosystem

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