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Carp virus provides significant insights into immunology

In an article published in the journal Nucleic Acids Research, the team led by Prof. Alain Vanderplasschen, a virologist and immunologist at the University of Liège, describes 10 years of research on how a carp virus uses a protein domain called Zalpha (Zα) to inhibit the host cell’s defense mechanisms.

26 Sep 2022

The biological advantages of sperm swimming in groups

Sperm actually swim better together when they are swimming against the current. Contrary to common belief, spermatozoa frequently cooperate to go through the female reproductive system in a variety of mammalian species, contradicting the notion that the fastest and fittest male reproductive cell wins the fertilization race.

22 Sep 2022

Modification of the lignin “chemical code”

According to a recent study, it is possible to genetically alter the lignin chemistry of plants to improve their ability to recover from drought without compromising the size of the plant or seed production.

22 Sep 2022

An analysis of old genes’ influence on sea anemones

For the neuronal cell types’ categorization as more complicated creatures, the genetic fingerprint of Nematostella vectensis—the sea anemone—reveals that the members of this evolutionarily very ancient animal phylum employ identical gene cascades.

22 Sep 2022

New imaging technologies to evade immune responses of Candida albicans

Researchers from the Monash Biomedicine Discovery Institute have demonstrated how the common fungus Candida albicans evades immune responses using newly discovered imaging technologies. The researchers claim that this involves a fungus that can shape-shift in an “alien-like” manner to escape immune cells.

21 Sep 2022

Understanding the structure of the nucleus inside a cell using mathematics

Recent work shows a novel mathematical approach to start comprehending how a cell’s nucleus is structured.

21 Sep 2022

Soil viruses contribute auxiliary functions to their hosts

There are billions of fungi, bacteria, and viruses, in a handful of soil, all working to support the cycle of life. Comprehending the interaction of these microbes with one another aids researchers evaluate soil carbon and nutrient cycling, soil health, and also the means through which dead insects decompose.

21 Sep 2022

Native 3D structure of the ciliary base witnessed for the first time

Because flaws in the cilia transport system can result in, for example, blindness or cystic kidneys, findings reported in Science offer new understandings of the molecular basis for different diseases.

20 Sep 2022

Researchers reveal key developmental difference between the brains of modern humans and Neanderthals

AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neanderthals, due to the change of a single amino acid in the protein TKTL1.

From The Max Planck Institute 20 Sep 2022

DCNNs are insensitive to object configuration

According to professor James Elder, co-author of a York University paper, Deep convolutional neural networks (DCNNs) could not view objects in the same way that humans do (through configural shape perception), which could be harmful in real-world AI applications.

From York University 19 Sep 2022

Novel molecular mechanism of focal adhesion kinase inhibition in HD

Principal researchers at the Brain Science Institute (BSI) of the Korea Institute of Science and Technology were said to have discovered substantially decreased activity of focal adhesion kinase (FAK) proteins that play a significant role in neurite motility and proper synapse formation in HD patients’ brain tissues.

19 Sep 2022

Studying cell membranes’ role in allowing viruses’ spike proteins to infect cells

University of Alberta’s study demonstrates the way cell membranes perform a much bigger role than that was understood in enabling spike proteins on viruses to affect cells.

19 Sep 2022

Researchers claim AI could produce protein molecules

Machine learning has completely changed protein structure prediction over the past two years. A comparable revolution in protein design is now described in three studies published in Science.

16 Sep 2022

Novel computational tool integrates available biological data

The amount of biological data that is currently available has increased exponentially in recent decades as a result of the quick development of the various disciplines in the fields of biological and biomedical research (like genomics, proteomics, and transcriptomics).

16 Sep 2022

Unique combination of transcription factors trigger cell regeneration in zebrafish

Scientists at the National Institutes of Health have identified a particular protein network required for cell regeneration to restore hearing in zebrafish.

From National Human Genome Research Institute (NHGRI) 15 Sep 2022

Researchers use bacteria to create artificial cells that function like living cells

Researchers have used bacteria to create sophisticated synthetic cells that imitate the activity of genuine cells.

15 Sep 2022

Researchers analyze how clusters of molecules meet inside cells

A developing area studies how clusters of molecules gather inside of cells, similar to how oil droplets form and separate from the water in a vinaigrette.

From New York University (NYU) 15 Sep 2022

Encouraging breakthroughs in eliminating therapy-resistant cancer cells

The human immune system is notably adept at evading tumor cells, which construct physical barriers, adopt masks, and restrain the immune system with molecular ploys.

14 Sep 2022

Studies highlight bacteria accelerate the leukemia development in mice through specific viruses

By helping with digestion, supplying nutrients and metabolites, and collaborating with the immune system to ward off pathogens, gut bacteria have a significant impact on health.

14 Sep 2022

Human-specific gene involves in neocortical expansion during evolution

Great ape animal experiments have long been prohibited in Europe due to ethical concerns. An alternative to using animals in investigations is the use of organoids, which are three-dimensional cell structures that can be generated in the lab and are only a few millimeters in size.

From The Max Planck Institute 14 Sep 2022