Cell Death News and Research

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Scientists unravel the proteins that trigger some cancerous tumors

Even on a good day, DNA is constantly getting damaged. Nicks, scratches, breaks: the delicate strands that carry life's genetic code take a beating as they jumble about in the course of their work. If left untreated, errors accumulate, with fatal consequences -- such as cancerous tumors -- for the cell and the organism.

11 Jun 2021

Novel protein could improve treatment outcomes after heart attacks

New research, headed by scientists from Washington State University, has revealed a protein that could be crucial for enhancing treatments after a heart attack.

4 Jun 2021

Scientists discover the central role of LRRC8A gene in cellular ability to survive osmotic shock

Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate a mechanism that allows them to recover their initial water volume and avoid dying.

2 Jun 2021

Study discovers novel function for metabolic enzyme medium-chain acyl-CoA dehydrogenase

Scientists have come up with an innovative function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM).

1 Jun 2021

Exposure to even low levels of lead can trigger epigenetic changes

A research team from Brazil and Portugal has identified a link between a microRNA (miRNA) and the presence of lead in an organism.

18 May 2021

Study analyzes how resistance proteins defend plants from pathogens

Disease resistance proteins function as main immune receptors in plants, detecting pests and pathogens and initiating robust defense responses.

13 May 2021

Study reveals mitochondrial enzyme plays a vital role in preventing ferroptosis

According to a study, the mitochondrial enzyme DHODH plays a significant and previously unknown function in preventing a form of cell death called ferroptosis.

13 May 2021

Researchers devise a small-molecule cocktail to protect stem cells from stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

Researchers identify specific proteins that play a key role in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease.

3 May 2021

Critical intermediate in normal cellular metabolism may lead to cell death

A recent study shows that a critical intermediate in normal cellular metabolism is also a cause for cell death in the right sense.

27 Apr 2021

Study shows a possible link between pesticide exposure and increased COVID-19 susceptibility

Researchers have discovered a possible connection between increased vulnerability to COVID-19 infection and exposure to organophosphate pesticides.

27 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

From Institut Pasteur 23 Apr 2021

Inhibiting a specific protein could increase tumor sensitivity to PARP inhibitors

Researchers at the Francis Crick Institute have found that blocking a specific protein could increase tumor sensitivity to treatment with PARP inhibitors. Their work published in Science , suggests combining treatments could lead to improved therapy for patients with inheritable breast cancers.

9 Apr 2021

Cell Death News and Research

Scientists unravel the proteins that trigger some cancerous tumors

Novel protein could improve treatment outcomes after heart attacks

Scientists discover the central role of LRRC8A gene in cellular ability to survive osmotic shock

Study discovers novel function for metabolic enzyme medium-chain acyl-CoA dehydrogenase

Exposure to even low levels of lead can trigger epigenetic changes

Study analyzes how resistance proteins defend plants from pathogens

Study reveals mitochondrial enzyme plays a vital role in preventing ferroptosis

Researchers devise a small-molecule cocktail to protect stem cells from stress

New therapeutic target for patients with acute myeloid leukemia

Researchers identify specific proteins that play a key role in the development of dendritic cells

Critical intermediate in normal cellular metabolism may lead to cell death

Study shows a possible link between pesticide exposure and increased COVID-19 susceptibility

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Inhibiting a specific protein could increase tumor sensitivity to PARP inhibitors

Dopamine-releasing brain cells shed light on Parkinson’s disease

3D-printed system enables the growth of self-organizing brain tissue

High expression of cell death genes linked to increased risk of dying early from lung cancer

Innovative computational model of cells could help better understand neurodevelopmental disorders

Study reveals molecular mechanisms involved in eliminating unwanted cells in the body

Study maps structure, mechanism of membrane enzyme that has a role in chronic inflammation, cancer

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