Chemotherapy News and Research

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Chemotherapy, in its most general sense, is the treatment of disease by chemicals especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen.

Researchers find active protein in tumor cells might help in new cancer treatments

A discovery regarding how a particular protein is triggered in tumor cells, conducted by researchers at the University of California, Irvine, may lead to more effective therapies for some of the deadliest types of cancer.

20 Jul 2022

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Research highlights a novel technique for cancer cells to repair DNA damage

Researchers at the University of Birmingham have identified a novel mechanism for cancer cells to repair DNA damage.

23 May 2022

Scientists detect rare genetic signs of drug-resistant tuberculosis with the aim to stop disease progression

Many people believe tuberculosis (TB) is a disease of the past. Nonetheless, it claims over a million lives each year. Furthermore, the problem is escalating as Mycobacterium tuberculosis—the pathogen that causes tuberculosis develops resistance to the antibiotics used to treat the disease.

12 May 2022

Study shows new potential target for CAR T cells to inhibit solid tumors

CAR T therapy, or chimeric antigen receptor T-cell therapy, has revolutionized the treatment of some blood cancers, allowing patients with relapsed or refractory disease to live longer and better lives.

10 May 2022

Study underscores the crucial role of genomic profiling in diagnosing and grading brain tumors

Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy.

22 Apr 2022

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Extra copies of a piece of DNA partly explain insensitivity to chemotherapy in germ cell cancer, a new study shows.

21 Apr 2022

Researchers develop epigenetic methods for effective cancer treatments

If genetics is concerned with gene sequencing, epigenetics is concerned with how genes are employed (or not) by a cell.

19 Apr 2022

Vitamin E can reinvigorate dendritic cells to enhance immunotherapy responses

Combining a retrospective analysis of clinical records with in-depth laboratory studies, researchers at The University of Texas MD Anderson Cancer Center have discovered that vitamin E can enhance immunotherapy responses by stimulating the activity of dendritic cells in the tumor.

18 Apr 2022

Study reveals key characteristics of immune cells in ovarian cancer

Ovarian cancer is a difficult to diagnose malignancy that is often caught at a more advanced stage. Treatments for this cancer have changed little over the past few decades, with surgery and chemotherapy being the most common therapeutic approaches.

15 Apr 2022

Study shows how biodegradable gel helps immune system to keep cancer away

After tumors are surgically removed, a novel biodegradable gel increases the immune system’s capacity to keep cancer away.

11 Apr 2022

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

22 Mar 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

T cells sometimes remain in the skin for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

8 Mar 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

Study identifies a new cancer cell state related to poor treatment response in ovarian cancer patients

The prognosis for ovarian cancer patients is grim: less than half of high-grade serous ovarian cancer (HGSC) patients survive past five years from diagnosis. Initially, the tumors typically respond well to chemotherapy but become resistant after repeated treatments, enabling the cancer to regrow.

24 Feb 2022

New vaccine providing protection against future animal-to-human viral diseases may be possible

A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans -; including SARS-CoV-2, the cause of COVID-19 -; may be possible, say Johns Hopkins Medicine researchers, based on findings from their recent study.

17 Feb 2022

Novel method can report specific immune cell types using only DNA from blood

Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.

10 Feb 2022

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.

From Society for Laboratory Automation and Screening (SLAS) 27 Jan 2022