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Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

New study shows how neuroblastoma cells deal with rapid division

The cells of a certain tumor type, called neuroblastoma, divide very rapidly. This rapid division can have potentially fatal consequences for them. A new study shows how neuroblastoma cells deal with this dilemma.

1 Dec 2021

Cornell food scientists develop new tool to quantify zinc status within the body

Zinc deficiency is prevalent around the world, and among children, these mineral shortfalls can lead to stunting, embryonic malformations and neurobehavioral abnormalities.

26 Nov 2021

Study identifies key proteins that damage skin cells in psoriasis

Psoriasis is an autoimmune disease that is characterized by patches of red, inflamed skin and painful, scaly rashes.

25 Nov 2021

Deep learning can generate real insights into how proteins interact

Scientist are now combining recent advances in evolutionary analysis and deep learning to build three-dimensional models of how most proteins in eukaryotes interact.

23 Nov 2021

Experts develop new method to quantify the physiological status of zinc

The deficiency of Zinc is prevalent worldwide. The shortfall of this mineral in children leads to embryonic malformations, stunting, and neurobehavioral abnormalities.

19 Nov 2021

Study compares protein quality of meat-based burgers and plant-based burgers

Plant-based burgers claim that they offer protein similar to their animal-based counterparts. However, protein is expressed on present-day nutrition labels as a single generic value expressed in grams.

19 Nov 2021

De Novo Mutations may Play a Role in Male Infertility

In this interview, we speak to Dr. Miguel J. Xavier about his latest research into male infertility and how de novo mutations may play a part.

From Newcastle University 19 Nov 2021

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

Study identifies new gene that promotes progression to type 1 diabetes

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

17 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Research analyzes strengths and weaknesses of seed-supply systems to support forest restoration

With commitments to restore more than 47.5 million hectares of degraded land and forests by 2030, the Philippines, Indonesia, Malaysia and India hope to become exemplar land custodians.

15 Nov 2021

Microbiome discovery may help improve treatment for patients facing gut damage

University of Calgary researchers probing the gut -; "the inner tube of life" -; have for the first time discovered specific factors in its workings that in the future may help improve treatment for patients facing gut damage or gastrointestinal disease.

15 Nov 2021