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Study highlights novel approach for designing anti-viral drugs

Scientists are exploring a novel screening approach that concentrates on the recognition of virus-specific morphological changes in virus-infected cells.

4 Aug 2021

Researchers devise a new method for safer delivery of RNA drugs

Scientists have developed and tested a library of lipid-based compounds for the safe and effective delivery of RNA drugs to the lungs.

3 Aug 2021

Next generation automation lab achieves huge productivity gains

Eli Lilly and Company and their industry partners, including sample management specialists – Ziath, are speeding the discovery of new medicines through the fully automated Lilly Life Sciences Studio lab in San Diego, USA.

From Ziath Ltd 30 Jul 2021

Researchers develop a cost-effective and versatile approach for drug synthesis

Different factors influence the cost-effectiveness of drug synthesis, the amount of waste generated being one of those.

29 Jul 2021

Study shows how to unlock CRISPR’s potential to regulate many genes simultaneously

A new technique to regulate several genes in engineered yeast cells could pave the way for the highly efficient, sustainable production of bio-based products.

19 Jul 2021

Study discloses neuroprotective properties of aromatic turmerone and its derivatives

Scientists discovered that aromatic turmerone and its derivatives have a direct effect on the dopaminergic nerves.

16 Jul 2021

Synthesis of complete crenarchaeol molecule elucidates its structure

Crenarchaeol is a large, closed-loop lipid that is present in the membranes of ammonium-oxidizing archaea, a unicellular life form that exists ubiquitously in the oceans.

14 Jul 2021

Isoflavone diet plus metabolizing gut bacteria may provide protection against MS

A new University of Iowa study suggests that metabolism of plant-based dietary substances by specific gut bacteria, which are lacking in patients with multiple sclerosis (MS), may provide protection against the disease.

14 Jul 2021

Artificial intelligence facilitates empty well detection

Ziath reports on ground-breaking use of Artificial Intelligence that enables discrimination between empty wells in sample tube racks from wells with a tube present which may have an obscured or poorly rendered barcode.

From Ziath Ltd 6 Jul 2021

Study reveals novel enzyme vital for the production of bacterial tropone natural products

Microorganisms produce natural products, for example, as disease-causing virulence factors or as defense substances against predators and competitors.

5 Jul 2021

Experimental model reveals the protective role of antioxidants in neurodegenerative disorders

Researchers used a model to replicate the blood-brain barrier and successfully demonstrated how antibody guards the brain against inflammation.

2 Jul 2021

Deep machine learning adds to the knowledge of one million molecules’ bioactivity

The Structural Bioinformatics and Network Biology team at IRB Barcelona has developed a tool that predicts the biological activity of chemical compounds.

30 Jun 2021

Cancer cells use aging gene to establish a permanent footing in the tissue

Scientists have found how mutated cells support their chance to form cancer.

17 Jun 2021

Novel protein could improve treatment outcomes after heart attacks

New research, headed by scientists from Washington State University, has revealed a protein that could be crucial for enhancing treatments after a heart attack.

4 Jun 2021

Scientists discover the central role of LRRC8A gene in cellular ability to survive osmotic shock

Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate a mechanism that allows them to recover their initial water volume and avoid dying.

2 Jun 2021

A gene that impacts the development of bone cancer in children discovered

Researchers have discovered a gene, OTUD7A, that impacts the development of Ewing sarcoma, a bone cancer that occurs mainly in children.

2 Jun 2021

Worm cells sense metabolism changes to stimulate their defense against pathogens

Microbial infections form part of the wider repercussions of the COVID-19 pandemic, and researchers are focusing more on such infections.

1 Jun 2021

Light-controlled on/off switch can help reset the biological clock

The biological clock is present in almost all cells of an organism. As more and more evidence emerges that clocks in certain organs could be out of sync, there is a need to investigate and reset these clocks locally.

26 May 2021

Climate change could make railway infrastructure vulnerable to greater damages

Just half a degree Celsius less warming would save economic losses of Chinese railway infrastructure by approximately $0.63 billion per year, according to a new paper published by a collaborative research team based in Beijing Normal University and the Institute of Atmospheric Physics, Chinese Academy of Sciences, China.

24 May 2021

New drug-like compound designed to stop malaria in its tracks

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

13 May 2021