Drugs News and Research

RSS

Improved Mapping of Small-Molecule Binding Sites in Cells

Researchers at Scripps Research created a novel, high-resolution method for identifying putative treatment targets on proteins in living cells.

3 Jan 2024

EPFL Scientists Develop Platform for Orally Available Cyclic Peptide Drugs

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

29 Dec 2023

AI-Powered Drug Breakthrough: Insilico Unveils Potent FGFR2/3 Inhibitor for Solid Tumors

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

29 Dec 2023

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.

26 Dec 2023

Scientists Unravel the Mystery of Parkinson's Disease With 3D Protein Structures

Scientists at St. Jude Children's Research Hospital revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases.

26 Dec 2023

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

26 Dec 2023

New Cell Model Paves Way for Faster Treatments for Neuromuscular Diseases

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

20 Dec 2023

Researchers Uncover Previously Unknown Inactive Form of p38a Protein

p38a protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions.

20 Dec 2023

New AI-Generated Proteins Could Revolutionize Medicine and Beyond

A new study Dec. 18 in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring.

19 Dec 2023

Combating the Illegal Organ Trade with Bio-Printing

The World Health Organization (WHO) estimates that there are not enough legally available organs for transplantation to meet even 10% of worldwide demand.

19 Dec 2023

Study Delves into the Transmission of Antimicrobial Resistance Among Cockroaches

A recent study delves into the transmission of antimicrobial resistance (AMR) among cockroaches, shedding light on potential implications for AMR transmission in humans.

15 Dec 2023

Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023

The Complex Dynamics of Death and Reversibility

Defining death neurologically poses a challenging task. Rather than a specific moment marking the transition from life to death, it is a process spanning several minutes, sometimes reversible under certain conditions.

13 Dec 2023

Novel DNA Tension Probe Technology Offers Precise Measurement of Platelet Function

A novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods currently in use, an experimental study shows.

12 Dec 2023

Free AI Drug Discovery Course Surpasses 2,500 Users

An online course on Disease Modeling and Target Discovery launched 7 months ago by clinical stage generative artificial intelligence (AI)-driven biotechnology company Insilico Medicine has surpassed 2,500 users.

12 Dec 2023

Deciphering the Chemistry Behind Antibody Tetramerization

Novel insights into antibody aggregation are anticipated to pave the way for fresh avenues in both research and therapeutic applications.

11 Dec 2023

Unlocking the Mysteries of Fetal Brain Development

Cheryl Rosenfeld has dedicated three decades to investigating the transmission of biological information from mothers to babies during pregnancy.

6 Dec 2023

Algorithmiq Demonstrates Path to Quantum Utility with IBM

Algorithmiq, a scaleup developing quantum algorithms to solve the most complex problems in life sciences, has successfully run one of the largest scale error mitigation experiments to date on IBM’s hardware.

6 Dec 2023

Presage Biosciences and AstraZeneca Partner to Advance Immuno-Oncology Research for Head and Neck Cancer

Presage Biosciences, a pioneering translational oncology company whose mission is to use CIVO and spatial molecular profiling to understand the complexity of drug response in the tumor microenvironment (TME), has entered into an agreement with AstraZeneca, a global biopharmaceutical company.

1 Dec 2023

New Irreversible Inhibitor Overcomes Drug Resistance in Cancer Cells

The concept of irreversible inhibitors binding permanently to a target protein has garnered growing interest for potential applications in drug development.

30 Nov 2023

Drugs News and Research

Improved Mapping of Small-Molecule Binding Sites in Cells

EPFL Scientists Develop Platform for Orally Available Cyclic Peptide Drugs

AI-Powered Drug Breakthrough: Insilico Unveils Potent FGFR2/3 Inhibitor for Solid Tumors

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Scientists Unravel the Mystery of Parkinson's Disease With 3D Protein Structures

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

New Cell Model Paves Way for Faster Treatments for Neuromuscular Diseases

Researchers Uncover Previously Unknown Inactive Form of p38a Protein

New AI-Generated Proteins Could Revolutionize Medicine and Beyond

Combating the Illegal Organ Trade with Bio-Printing

Study Delves into the Transmission of Antimicrobial Resistance Among Cockroaches

Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

The Complex Dynamics of Death and Reversibility

Novel DNA Tension Probe Technology Offers Precise Measurement of Platelet Function

Free AI Drug Discovery Course Surpasses 2,500 Users

Deciphering the Chemistry Behind Antibody Tetramerization

Unlocking the Mysteries of Fetal Brain Development

Algorithmiq Demonstrates Path to Quantum Utility with IBM

Presage Biosciences and AstraZeneca Partner to Advance Immuno-Oncology Research for Head and Neck Cancer

New Irreversible Inhibitor Overcomes Drug Resistance in Cancer Cells

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

Latest in Genomics