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Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Components leaking from broken muscle fibers activate 'satellite' muscle stem cells

While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.

13 Oct 2020

Severe cases of COVID-19 resemble systemic lupus erythematosus

Scientists from Emory Health Sciences have been observing an intense stimulation of immune cells in severe cases of COVID-19 disease. This activation of immune cells is similar to acute flares of systemic lupus erythematosus (SLE)—an autoimmune disease.

13 Oct 2020

Researchers test the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Virologists at the KU Leuven Rega Institute have been working on two lines of SARS-CoV-2 research: searching for a vaccine to prevent infection, and testing existing drugs to see which one can reduce the amount of virus in infected people.

12 Oct 2020

Developing a 'Trojan Horse' nanotherapy to fight breast cancer

With a nearly $2.6 million grant from the National Institutes of Health, Michigan State University researchers are using nanoscopic particles to turn the body's own cells into weapons that cancer won't see coming.

12 Oct 2020

UMD researchers use AI tools to predict how and when proteins form different shapes

By applying natural language processing tools to the movements of protein molecules, University of Maryland scientists created an abstract language that describes the multiple shapes a protein molecule can take and how and when it transitions from one shape to another.

12 Oct 2020

Researchers develop a new assembler for decoding genomes of microbial communities

Researchers from the Center for Algorithmic Biotechnology at St Petersburg University, as part of a group of Russian and American scientists, have developed the metaFlye assembler.

9 Oct 2020

Safe, efficient concentration of low volume samples with BioChromato's Smart Evaporator C1

BioChromato Inc. reports how the Department of Bioimaging Information Analysis at Gunma University is benefiting from the ability of its Smart Evaporator C1 to safely and efficiently concentrate low volume samples.

From BioChromato Inc. 9 Oct 2020

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine.

9 Oct 2020

Study shows thymoquinone compound selectively kills prostate cancer cells

According to a new study reported in the Oncogene journal, the thymoquinone (TQ) compound selectively destroys prostate cancer cells at advanced phases.

9 Oct 2020

New approach to determine the structure of large RNA molecules

Researchers have designed a new technique to establish the structures of huge RNA molecules at high resolution.

9 Oct 2020

Researchers identify specific neurons that may contribute to epileptic seizures

Epilepsy, results from impairment in brain cells and is often treated with drugs that counteract or control the seizures.

9 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Drugs News and Research

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

Components leaking from broken muscle fibers activate 'satellite' muscle stem cells

Severe cases of COVID-19 resemble systemic lupus erythematosus

Researchers test the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Developing a 'Trojan Horse' nanotherapy to fight breast cancer

UMD researchers use AI tools to predict how and when proteins form different shapes

Researchers develop a new assembler for decoding genomes of microbial communities

Safe, efficient concentration of low volume samples with BioChromato's Smart Evaporator C1

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

Study shows thymoquinone compound selectively kills prostate cancer cells

New approach to determine the structure of large RNA molecules

Researchers identify specific neurons that may contribute to epileptic seizures

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

New method reveals structural data of membrane proteins in explicit detail

Researchers develop new testing platform for breast cancer cells

Imaging technique could replace invasive tissue biopsies to determine cancer drug resistance

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

New drug shows promise in the treatment of neuroblastoma

New method can help test vaccine formulations

Fly larvae extract could protect plants from pathogenic bacteria

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