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Newly developed biodegradable microneedles deliver genes into the skin

Gene therapy offers an excellent potential for treating specific types of genetic defects and cancer, immunological diseases, infections, and wounds.

9 Oct 2020

Microneedles For Therapeutic Gene Delivery

There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections.

7 Oct 2020

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib.

7 Oct 2020

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

Researchers discover how synapses find energy to support intense neural conversations

Our thoughts, feelings, and movements are controlled by billions of neurons talking to each other at trillions of specialized communication points called synapses.

6 Oct 2020

80-year-old antibiotic redesigned for new medical uses

Physicians and scientists have long searched the natural world for chemicals that can improve human health.

5 Oct 2020

New platform can enhance the efficiency of cancer immunotherapy

Antibody-based immunotherapy is one of treatment options for cancer immunotherapy by modulating our immune system with therapeutic antibodies.

30 Sep 2020

New precision drug targeting cancer's ability to repair DNA shows promise

A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial - highlighting the potential of a new class of drugs known as ATR inhibitors.

29 Sep 2020

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival. (1-3)

24 Sep 2020

Combination treatment improves outcomes in advanced kidney cancer patients

An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. The pivotal study could lead to a new treatment option for patients with metastatic kidney cancer.

24 Sep 2020

New brain-inspired nanodevice can identify mutations in viruses

In the September issue of the journal Nature, scientists from Texas A&M University, Hewlett Packard Labs and Stanford University have described a new nanodevice that acts almost identically to a brain cell.

24 Sep 2020

Study shows removal of specific gene makes poxviruses harmless

According to a new study, the removal of a single gene makes poxviruses—a lethal family of viral infections that spread from animals to humans—harmless.

From University of Surrey 22 Sep 2020

Enhancing the effectiveness of immunotherapy against melanoma

Researchers at the University of Bern have discovered a mechanism in the body’s own immune system which is responsible for the maturation and activation of immune cells.

21 Sep 2020

Defined regulatory framework needed for developing live biotherapeutic products

The Pharmabiotic Research Institute (PRI), Europe's only regulatory expertise centre for the development of microbiome-based drug products, has announced the publication of a review titled "Live biotherapeutic products: the importance of a defined regulatory framework".

18 Sep 2020