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Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

A preclinical study performed by Monash University researchers discovered that utilizing a combination of phages and antibiotics to treat bacterial infections may be considerably more successful than using the drugs separately.

12 May 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Scientists get a clearer and more accurate image of proteins

Proteins are among the most significant and diverse biomolecules found in living organisms. These strings of amino acids, which take on complex 3-dimensional structures, are required for tissue growth and maintenance, the activation of thousands of biochemical events, and the immune system’s defense against invaders.

3 May 2022

Understanding the regulation of intramembrane proteases across the tree of life

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

27 Apr 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

Pharmaceuticals, plastics, and other industries use enzymes to help synthesize molecular feedstocks.

19 Apr 2022

Max Planck researchers reveal the structure of kinetochore corona

During cell division in a mother cell, the 23 chromosomes that carry the human genome must be first copied and later delivered to two newly forming daughter cells.

From The Max Planck Institute 11 Apr 2022

Scientists gain fascinating insights into the dynamic ultrastructure of the heart

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.

11 Apr 2022

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

In new research, UT Southwestern scientists report that imaging a key immunity protein known as STING at near-atomic resolution reveals a previously undiscovered binding location that appears to be crucial for launching immunological attacks.

11 Apr 2022

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

7 Apr 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

From New York University (NYU) 4 Apr 2022

Research reveals how a building block protein assembles to form poxvirus scaffold

Researchers at the Okinawa Institute of Science and Technology Graduate University have revealed how poxviruses build their scaffold - a temporary protein coat that forms and disappears as the virus matures.

1 Apr 2022

Plant biologists determine molecular ‘blueprint’, showing how plants observe light

For survival, plants depend on their ability to detect light. Plants, unlike animals, do not have photoreceptors in their eyes to receive and transmit messages from visual inputs.

1 Apr 2022

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

22 Mar 2022

Researchers use GP2 and UMOD to prevent urinary tract infection

A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.

16 Mar 2022

Cryo-EM reveals how a bacterial protein senses and rescues stalled ribosomes

As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins.

11 Mar 2022

Scientists observe first high-resolution 3D image of muscle protein nebulin

Skeletal and heart muscle owe their function as stable biological machines to the outstanding accuracy with which their sarcomeres are assembled.

22 Feb 2022

Study develops AI-based method to help analyze protein complexes

A new technique for analyzing proteins has been developed by researchers at Martin Luther University Halle-Wittenberg (MLU) and the European Molecular Biology Laboratory in Hamburg.

21 Feb 2022

3D structure of protein channel helps shed light on sensitive touch response of Venus fly traps

Scientists at Scripps Research have revealed the three-dimensional structure of Flycatcher1, an aptly named protein channel that may enable Venus fly trap plants to snap shut in response to prey.

18 Feb 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022