Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Fusion protein found to effective at treating pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is an insidious disease. Symptoms may begin slowly, and even before they appear, extensive damage has caused the obstruction of small arteries leading to increased blood pressure in the lungs.

22 Jul 2020

New technique increases the precision of gene editing

A group of biomolecular engineers from Rice University has now identified a C-worthy method that significantly improves the precision of gene editing.

17 Jul 2020

The immune system can play a key role in improving recovery from heart attacks

International research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

14 Jul 2020

New technology can improve treatment for cystic fibrosis

World-first research led by Monash University could hold the key to better monitoring and treatment of lung disease associated with cystic fibrosis (CF) - a condition thousands of people are diagnosed with each year.

14 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

How upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Chemist Develops Potential Drug To Treat Type 2 Diabetes Without Harsh Side Effects

Professor Dr. Robert P. Doyle has developed a new drug to treat type 2 diabetes in millions of patients who are seeking to better control their blood sugar.

24 Jun 2020

Study uncovers new genetic variants linked to type-2 diabetes

After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration's Corporal Michael J. Crescenz Veterans Affairs Medical Center found hundreds of genetic variants never before linked to the disease.

24 Jun 2020

Using CAR T cells to target senescence-related diseases

Chimeric antigen receptor (CAR) T cells have transformed the treatment of refractory blood cancers. These genetically engineered immune cells seek out and destroy cancer cells with precision.

19 Jun 2020

Cloning stem cells to create new treatments for Crohn's disease

For over a decade Wa Xian, research associate professor of biology and biochemistry at the University of Houston Stem Cell Center, has been perfecting technology for cloning stem cells.

19 Jun 2020

Study shows senotherapy blunts the progression of liver tumors

According to a new study performed by researchers, “senotherapy” blunts the progression of liver tumor in animal models.

22 May 2020

Smokers More Likely To Express ACE2 Protein That SARS-COV-2 Uses

Researchers report that smoking increases the gene expression of ACE2, the protein that binds SARS-CoV-2, which may promote COVID-19 infection.

19 May 2020

New antimicrobial peptide proves more effective in fighting drug-resistant bacteria

Through serendipity, researchers at the University of Pittsburgh Graduate School of Public Health considerably reduced the toxicity of a potential antibiotic against the most feared drug-resistant bacteria, while also improving its stability in fighting infections.

4 May 2020

Advanced simulations show how to improve efficiency of gene therapy

Diseases with a genetic cause could, in theory, be treated by supplying a correct version of the faulty gene.

20 Apr 2020

Single-cell cloning can lead to new therapies for COPD

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of death around the world. Now, two internationally acclaimed stem cell experts have discovered a large number of abnormal stem cells found in the lungs of COPD patients.

16 Apr 2020

Researchers develop 3D cultured cells that mimic liver fibrosis

Headed by researchers from Japan-based Tokyo University of Agriculture and Technology (TUAT), a group of scientists has effectively established three-dimensional (3D) cultured tissue that imitates liver fibrosis, which is a major trait of non-alcoholic steatohepatitis (NASH).

2 Apr 2020

Patients with chronic myopathy can benefit from cell-aging drug and exercise

According to a researcher from Hokkaido University and collaborators from Japan-based Sapporo Medical University, exercise can boost strength in muscle-degenerating disorders only when aging occurs in a certain type of muscle cell.

1 Apr 2020