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New nano-sized particles can improve the detection of tumors within the body

Nano-sized particles have been engineered in a new way to improve detection of tumors within the body and in biopsy tissue, a research team in Sweden reports.

3 Jun 2021

Scientists discover the central role of LRRC8A gene in cellular ability to survive osmotic shock

Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate a mechanism that allows them to recover their initial water volume and avoid dying.

2 Jun 2021

Worm cells sense metabolism changes to stimulate their defense against pathogens

Microbial infections form part of the wider repercussions of the COVID-19 pandemic, and researchers are focusing more on such infections.

1 Jun 2021

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

New microscope helps observe the whole body of the embryo

A research group led by Takashi Saito, of the Ehime University Graduate School of Medicine, developed a 2-photon excitation light-sheet fluorescence microscope which (1) lowers phototoxicity, (2) extends the field of view, and (3) heightens spatial resolution.

31 May 2021

Digital tool predicts protein stability in a cheaper, safer, and faster way

A cutting-edge digital tool that will make it cheaper, safer and faster for pharmaceutical companies to predict protein stability - a vital step in the development of new medicines - is being rolled out by scientists from the UK's University of Bath through their spin-out company, BLOC Labs.

From University of Bath 31 May 2021

Researchers study the mechanical properties of prostate cancer cells treated with anti-cancer drugs

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow.

28 May 2021

New plasmofluidic chip could accelerate diagnosis during current and future pandemics

Reverse transcription-polymerase chain reaction (RT-PCR) has been the gold standard for diagnosis during the COVID-19 pandemic.

27 May 2021

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

Study establishes link between heat stress and crop yield

Scientists report that it is possible to detect and predict heat damage in crops by measuring the fluorescent light signature of plant leaves experiencing heat stress.

25 May 2021

Researchers develop an unprecedentedly flexible new DNA staining probe

A team of scientists at Nagoya University in Japan has invented an extremely versatile DNA fluorescent dye called “Kakshine".

17 May 2021

New probe allows real-time imaging of molecular orientations in live cells

Monitoring alignments of the building blocks of cells is important to understand how the cells are built. By collaborating with imaging scientists at the MBL, researchers from Japan have developed a new probe which they call POLArIS, allowing real-time imaging of molecular orientations in live cells.

17 May 2021

Mutant corn gene found to increase the amount of sugars in the seeds and leaves

An abnormal accumulation of carbohydrates—starches and sugars—in the kernels and leaves of a mutant line of corn can be traced back to a single misregulated gene, and this finding provides insights into how the plant responds to stress.

From Penn State University 5 May 2021

Genetically encoded sensor helps detect hallucinogenic substances

Researchers at the University of California, Davis, have created a genetically encoded sensor for detecting hallucinogenic substances.

From The University of California, Davis 29 Apr 2021

Researchers discover new approach to reform plant breeding and genetics

The research was conducted at the Department of Food Science at the University of Copenhagen (UCPH FOOD) with professor emeritus Lars Munck as coordinator and builds on earlier work since 1963 at Svaloef Plant Breeding Institute and the Carlsberg Laboratory.

28 Apr 2021

Developing a portable tool to detect street drug ‘spice’

AZoLifeSciences speaks to researchers from the University of Bath about their latest research that led to the development of a device that can detect 'spice'.

From University of Bath 28 Apr 2021

Study reveals RNA regulatory mechanisms within transcription-translation couplings

To gain a better understanding of how bacterial RNA gives rise to proteins scientists are now focusing on the special way this process takes place in bacteria.

15 Apr 2021

New fluorescent probe that can discriminate B lymphocytes over T lymphocytes

Human blood contains several different components, including plasma, red blood cells (RBCs), white blood cells (WBCs), and platelets.

15 Apr 2021

Microfluidic probe sends free radicals on live cells

Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging.

7 Apr 2021

Unique mini-microscope enables imaging of brain activity in freely moving mice

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days.

6 Apr 2021