Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Study identifies DNA alterations that underpin brain and cognitive decline in the elderly

According to a new mathematical model published recently in eLife, Alzheimer’s disease has some important similarities with healthy aging.

20 May 2021

Successful class of therapeutics attack and shut down unique and harmful genes

A potential class of therapeutics that uses synthetic nucleic acids to attack and shut down harmful genes while preventing viral spread is gathering momentum.

18 May 2021

Supercoiling characteristic of DNA's structure controls gene expression, research shows

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling that needs to be resolved later.

10 May 2021

Highly efficient method to identify the genetic “switches” that control gene expression

Scientists have created a high-throughput method to help explain and regulate gene expression for the treatment of diseases like beta-thalassemia and sickle cell disease.

7 May 2021

Study unravels a crucial element that influences gene expression in blood stem cells

A complex network of biochemical pathways keeps the living organism healthy and alive.

From National University of Singapore (NUS) 7 May 2021

“Chemical nose” smells vital variations in unusual folding of DNA structures

Small variations in the structure of DNA have been related to breast cancer and other diseases, but they have been incredibly hard to find so far.

6 May 2021

New atlas may support present and future conservation efforts to protect coral reefs

A team of researchers has created the world’s first atlas of all the different types of cells in a reef-building stony coral that inhabits the Indo-Pacific oceans.

5 May 2021

New genetic database maps how immune disorders evolve

A first-of-its-kind genetic database for autoinflammatory and autoimmune disorders has been created by Japanese researchers.

4 May 2021

Researchers study the unique genomic organization of coral symbionts

According to recent findings, the genome of single-celled plankton, called dinoflagellates, is arranged in an extremely unusual and strange manner. The study results set the foundations for further research into these vital aquatic species and significantly broaden the understanding of what a eukaryotic genome can look like.

3 May 2021

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Study identifies single protein key to regulating sex differences in Parkinson’s disease

Neuroscientists have found that a single protein is critical to controlling sex disparities in the brain’s susceptibility to age-related neuron loss.

From University of Pittsburgh 29 Apr 2021

Study reveals SARS-CoV-2 spike protein can trigger long-term gene expression changes

According to the findings of a recent cell study, the SARS-CoV-2 spike protein can trigger long-term gene expression changes.

29 Apr 2021

New chemical tool elucidates how proteins recognize and associate with one another

A University of Hong Kong research team has created a novel chemical method for illustrating protein interaction networks in cells.

29 Apr 2021

Researchers discover new approach to reform plant breeding and genetics

The research was conducted at the Department of Food Science at the University of Copenhagen (UCPH FOOD) with professor emeritus Lars Munck as coordinator and builds on earlier work since 1963 at Svaloef Plant Breeding Institute and the Carlsberg Laboratory.

28 Apr 2021

New, altered form of prolactin receptor found to drive breast cancer

Prolactin is a hormone that has long been thought to play an important role in breast development and growth, as well as milk production during pregnancy.

27 Apr 2021

New algorithm maps gene expression patterns into specific locations

Cell-type databases are increasing in size and complexity as researchers accumulate a great deal of gene-sequencing data.

21 Apr 2021

Study: Interaction between distant parts of RNA can regulate gene expression

Russian researchers have now investigated the role of double-stranded fragments of the maturing RNA and demonstrated that the interaction between faraway parts of the RNA can control gene expression.

20 Apr 2021

New CRISPR technology allows scientists to switch off any gene in human cells

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

19 Apr 2021

Study shows how stem cells make specific types of cells

With the help of a novel single-cell technique, researchers from the Walter and Eliza Hall Institute (WEHI) have revealed a new way to interpret the programming behind stem cells and how these cells make specific types of cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 16 Apr 2021

Growing chimeric embryos could offer new insights into developmental biology, evolution

Scientists from China and the United States have been able to grow chimeric embryos for a considerable period of time—of up to 20 days—by injecting human stem cells into primate embryos.

16 Apr 2021