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Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023

From Mice to Men: New Studies Bridge the Gap in Brain Cell Gene Expression Across Species

Despite all our cells sharing the same DNA, there are thousands of different cell types in the human brain, each with a unique structure and function.

14 Dec 2023

NSF Funds IWGSC Project to Sequence Ancient Bread Wheat Genomes for Improved Traits

The International Wheat Genome Sequencing Consortium (IWGSC) is starting a two-year project, with funding from the U.S. National Science Foundation (NSF), to mine an untapped genetic resource for wheat improvement by sequencing the genomes of ancient varieties representing the worldwide diversity of bread wheat.

14 Dec 2023

CRISPR Takes Probiotics to the Next Level

Humans can benefit significantly from symbiotic relationships with probiotics-;live bacteria and microorganisms that influence the gut microbiota.

14 Dec 2023

Unveiling ppGpp’s Surprising Role in Fruit Fly Sleep

Sleep, a fundamental behavior observed across various organisms, ranging from worms to humans, is influenced by both internal sleep drive and external environmental factors.

12 Dec 2023

Unveiling the Role of Exosomes in Regulating Hepatic Lipid Metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by an excess accumulation of hepatic lipids, is highly prevalent and can progress to cirrhosis and liver cancer.

12 Dec 2023

Zika's Enzyme Cascade Holds the Key to Viral Replication

Viruses operate with limited genetic material and a sparse protein repertoire, requiring efficient utilization of their components. The Zika virus serves as an illustrative case, producing only 10 proteins.

11 Dec 2023

Fossil Lipids and Genetics Offer Glimpse into Early Animal Diets

Paleontologists are gaining insight into life from over a billion years ago by analyzing chemical remnants in ancient rocks and studying the genetics of present-day animals.

11 Dec 2023

Study Reconstructs Genomic History of the Balkan Peninsula

A multidisciplinary study led by the Institute of Evolutionary Biology in Spain (a joint center of the Spanish National Research Council and Pompeu Fabra University), the University of Belgrade in Serbia, the University of Western Ontario in Canada, and Harvard University in the USA, reconstructs the genomic history of the Balkan Peninsula during the first millennium of the common era, a time and place of profound demographic, cultural and linguistic change.

8 Dec 2023

Researchers Redesign the Future of mRNA Therapeutics

Scientists have unearthed that errors in the interpretation of therapeutic mRNA by the cell’s decoding apparatus can incite an inadvertent immune reaction within the body.

7 Dec 2023

Revealing Electric Eels' Role in Environmental DNA Transfer

The electric eel holds the title of Earth’s most powerful electricity-producing creature, boasting the ability to unleash up to 860 volts—enough to power machinery.

6 Dec 2023

Brain Cell Genetics Drive Alzheimer's Progression

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

6 Dec 2023

Unraveling the Complexities of Gene Regulation with MAbID

A novel technique named MAbID, developed by researchers led by Jop Kind, has been introduced to concurrently investigate various mechanisms of gene regulation, crucial for both development and disease processes.

5 Dec 2023

Unraveling the Genomic Secrets of Magic Mushrooms

Researchers have compiled genome data for numerous strains and varieties of “magic mushrooms,” aiming to understand the impact of domestication and cultivation on their genetic makeup.

5 Dec 2023

Study Elucidates How Mutant NPM1 Protein Drives Leukemia by Activating Autophagy System

In a recent study, scientists led by Professor Stefan Müller from Goethe University's Institute of Biochemistry II investigated a specific form of blood cancer known as acute myeloid leukemia, or AML.

5 Dec 2023

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

5 Dec 2023

Johnson Matthey Announces Partnership With Basecamp Research to Accelerate the Adoption of Biocatalysis Solutions

Johnson Matthey (JM), a global leader in sustainable technologies, and Basecamp Research, a leader in mapping biodiversity for computational bio-design, today announced their partnership to accelerate the adoption of more sustainable, bio-based catalysts.

From Johnson Matthey 5 Dec 2023