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Experts develop CRISPR-Cas9-mediated inheritance control in male mice

The world’s first CRISPR-Cas9 genetic editing-based strategy to regulate inheritance in mammals was declared nearly three years ago.

From UC San Diego 13 Jan 2022

Scientists develop DNA-based fluorescent nanoantenna to evaluate protein activity

Researchers at the Université de Montréal have developed a nanoantenna to track protein movements.

13 Jan 2022

Researchers cultivate an archaeon that breaks down oil all by itself

Microbes are capable of converting oil into natural gas, i.e., methane.

From The Max Planck Institute 23 Dec 2021

Driving up the immune response at tumor site may help boost immunotherapy

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

15 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

Scientists unravel the structure of octopus-like Lassa viral polymerase

Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.

7 Dec 2021

New study shows how neuroblastoma cells deal with rapid division

The cells of a certain tumor type, called neuroblastoma, divide very rapidly. This rapid division can have potentially fatal consequences for them. A new study shows how neuroblastoma cells deal with this dilemma.

1 Dec 2021

Researchers use X-ray from 3rd synchrotron facility to analyze 3D structure of chromosomes

Threads or earphone cables placed in tight spaces get easily tangled. On the contrary, our body's long and loose DNA packs into rod-shaped chromosomes one-millionth its size when the cell divides.

30 Nov 2021

Experts analyze key protein complexes involved in DNA replication and repair

Cryogenic electron microscopy (cryo-EM) allows scientists to investigate the assembly of DNA replication machinery where DNA is damaged.

25 Nov 2021

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

Cellular senescence is caused by irreversible damage to the genome

Researchers have demonstrated that the aging of cells is dependent on a genomic instability mechanism that causes the disease.

15 Nov 2021

Study uses artificial evolution to search DNA molecules for light producing deoxyribozymes

Once thought to function primarily as a storage molecule for genetic information, it is now known that DNA can also catalyze chemical reactions. Although such DNA enzymes (deoxyribozymes) have not been identified in nature, they can be isolated in the lab using powerful methods of artificial evolution.

22 Oct 2021

Decoding the large and complex onion genome

"In this study, we challenged the limits of how far we can go in deciphering a DNA sequence consisting of 16 billion base pairs," said paper author Masayoshi Shigyo, professor in the Laboratory of Vegetable Crop Science, Graduate School of Sciences and Technology for Innovation, Yamaguchi University, and researcher at the National Institutes of Natural Sciences.

8 Oct 2021

Plant responses to light can be altered to encourage food growth

Scientists have figured out how plants respond to light and can flip this genetic switch to encourage food growth. The discovery could help increase food supply for an expanding population with shrinking opportunities for farming.

7 Oct 2021

Active genes do not form clusters and share resources during early development in fruit flies

Active genes do not form clusters and share resources during early development in the fruit fly, according to a new study by New York University and Princeton researchers published in the journal Current Biology.

6 Oct 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, shows study

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021