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Novel Replacement Strategy Opens the Door to Therapeutic Interventions for Genomic Diseases

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development.

27 Oct 2023

Unraveling the Impact of Genetic Mutations on Future Generations

Regarding the structure of the human genome, it is only a matter of time until detrimental genes, which have the potential to jeopardize future generations, emerge within a population.

26 Oct 2023

New Insights Into the Role of Autophagy in Yeast Aging

Aging is an inevitable process that impacts all cell types, making yeast cells a common choice as a model organism in aging research.

26 Oct 2023

Novel Gene Therapy Approach Delivers Large Genes

A breakthrough by University of Zurich (UZH) researchers introduces a versatile technique for efficiently and safely delivering substantial genes, holding significant promise for therapeutic applications.

25 Oct 2023

Shark Survival Through the Ages: Unveiling Genetic Secrets

Sharks, having thrived for millions of years, exhibit a rare susceptibility to cancer while displaying heightened sensitivity to environmental shifts.

24 Oct 2023

Software Tool Paves the Way for Safer CRISPR Genome Editing

Researchers have developed a groundbreaking software tool known as DANGER analysis, offering a solution for safer and more precise genome editing.

23 Oct 2023

Reassessment of the Role of Background Mutations in Genome Editing

More than a thousand years ago, tomatoes evolved through natural mutations. After human evolution, they cherry-picked tomatoes with preferred traits.

20 Oct 2023

The Story of Sapiens and Neanderthals as Told by Genomes

Neanderthals, who had lived for hundreds of thousands of years on the western half of the Eurasian continent, gave way to Homo sapiens, who had come from Africa, some 40,000 years ago.

19 Oct 2023

Study Uncovers New Mechanism for Plant-Microbe Communication

Microorganisms that live on or in plant tissues form what is known as a plant microbiome. This interface plays an important role in plants' survival due to the existence of beneficial microorganisms.

19 Oct 2023

"Old School" Genetics may be Just Fine for Species Conservation, Study Suggests

In the world of threatened and endangered species conservation, the genomic revolution has raised some complicated questions: How can scientists justify assessing species genetic diversity without consulting entire genomes now that they can be sequenced?

17 Oct 2023

MIT Chemists Discover Structure of SARS-CoV-2 Ion Channel in Open State

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

16 Oct 2023

Study Discovers Fanzors in Eukaryotic Organisms

Snails, algae, and amoebas all have programmable DNA-cutting enzymes called Fanzors, and a recent study from Massachusetts Institute of Technology’s (MIT) McGovern Institute for Brain Research has found hundreds of them.

16 Oct 2023

Study Uncovers Genes in Gut Microbe That Play Key Role in Early Colonization After Fecal Microbe Transplant

Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants,

16 Oct 2023

Identifying QTLs for Improved Nitrogen Use Efficiency in Eggplant

In the pursuit of sustainable agriculture, a key goal is to enhance nitrogen use efficiency (NUE) in crops.

16 Oct 2023

New Findings Suggest Endosymbiotic Origin of Apoptosis

Apoptosis, frequently described as programmed cell death, is a fundamental mechanism essential for the growth and development of multicellular organisms.

13 Oct 2023

Researchers Develop Drug Targeting lncRNA TUG1 to Control Brain Tumor Growth in Mice

A new study has unraveled a crucial link between how cancer cells cope with replication stress and the role of Taurine Upregulated Gene 1 (TUG1). By targeting TUG1 with a drug, the researchers were able to control brain tumor growth in mice, suggesting a potential strategy to combat aggressive brain tumors such as glioblastomas.

13 Oct 2023

The Powerful Limb Regeneration Capabilities of Axolotl

Researchers from EPFL shed light on the axolotl’s unrivaled limb regeneration ability, contradicting long-held assumptions and providing fresh insights into possible mammalian limb restoration.

12 Oct 2023

Researchers Unveil Novel Protein Families and Functions in Microbial Communities

Imagine researchers exploring a dark room with a flashlight, only able to clearly identify what falls within that single beam. When it comes to microbial communities, scientists have historically been unable to see beyond the beam -; worse, they didn't even know how big the room is.

12 Oct 2023

Increased Pain Sensitivity and Neanderthal Gene Variants

According to a recent study co-led by UCL researchers, those who contain three gene variations acquired from Neanderthals are more susceptible to specific types of pain.

11 Oct 2023

Uncovering the Genetic Landscape of Lactic Acid Bacteria

An international team of researchers has released the initial all-encompassing comparative analysis of the pan-genome of lactic acid bacteria (LAB), a group of microorganisms crucial to both natural ecosystems and the food industry.

11 Oct 2023