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New CRISPR RNA-guided Caspases could lead to promising antiviral and tissue engineering tools

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

26 Aug 2022

The correlation between high facial similarity and shared DNA

DNA analysis and a collection of photographs of genetically unrelated lookalikes have shown that strong facial likeness is tied to shared genetic variations. The article is published in Cell Reports on August 23rd, 2022.

25 Aug 2022

The complex link between pancreatic malformations and the “dark genome”

For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.

25 Aug 2022

Diseased connective tissue cells alter the physical structure of their genomes

Researchers at Penn Medicine have found that when cells are impacted by the disease, the physical structure of their genome changes.

25 Aug 2022

Researchers identify microbes that influence sorghum development during drought

Drought is one of the greatest threats to agricultural systems, resulting in unpredictable crop yields, declines in farm revenue, and an increase in disease outbreaks.

24 Aug 2022

Researchers discover a genome that provides an understanding of diterpenoids

Salvia officinalis (S. officinalis), known as sage or common sage, and the Chinese sage (S. miltiorrhiza), or Danshen (red sage) in Chines, pertain to the Lamiaceae family and have been grown for medicinal purposes for a long time in Europe and East Asia, respectively.

22 Aug 2022

Researchers face challenges with stem cell lines that carry major DNA damage

Stem cells are a type of cell that can be configured to transform into almost any sort of cell in the body. They are presently used in research on organ development as well as in the initial phases of embryo development.

15 Aug 2022

Parents transmit genetic and epigenetic information to their offspring

The knowledge of what can be inherited from parents and how their life experiences impact children could be completely rewritten if a fundamental finding concerning a factor driving healthy development in embryos were made.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 15 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Circadian clock impacts cell growth, metabolism, and tumor development

Scientists from the University of California, Irvine, have defined how the circadian clock impacts cell growth, metabolism, and tumor progression in a new study.

12 Aug 2022

Biotrophic fungus uses host auxin signaling pathway for its own purposes

Ustilago maydis attacks and reproduces in the aerial parts of the corn plant. At the location of the infection, massive tumor-like tissue growths frequently develop. The size of these galls can exceed that of a child’s skull.

12 Aug 2022

Self‑pollinating flowering plant quickly loses genetic variation without bumble bees

Without bumble bees, a flowering plant that can self-pollinate lost substantial genetic variation within only nine generations, an experimental study found.

11 Aug 2022

Researchers discover antibiotic resistance genes in M. tuberculosis

More than 10,000 different Mycobacterium tuberculosis bacteria isolated from 23 different countries were subjected to a thorough investigation, which uncovered new genes linked to resistance to 13 first- and second-line novel and repurposed medicines.

11 Aug 2022

Study provides guidelines on how to design safer CRISPR reagents

The 2020 Nobel Prize in Chemistry was awarded to Jennifer A. Doudna and Emmanuelle Charpentier for developing the widely utilized and incredibly precise genome editing method known as CRISPR/Cas9

11 Aug 2022

AI tools forecast DNA’s regulatory region and 3D structure

According to two recent research published in Nature Genetics, recently created artificial intelligence (AI) tools effectively identified the function of DNA’s regulatory regions and three-dimensional (3D) structure based only on its raw sequence.

9 Aug 2022

Study discovers a molecular mechanism that confers special physical properties to chromosomes in dividing human cells

The Gerlich Group at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) has identified a molecular process that gives chromosomes in dividing human cells unique physical characteristics that permit faithful transmission to the progeny.

8 Aug 2022

Scientists solve how RNA molecules reach their targets

Scientists claim that life does not come with an instruction manual, but this is not totally accurate. Each cell in our body follows the instructions provided by its DNA in the form of RNA molecules.

1 Aug 2022

A Retro-Cascorder device records a cell’s genetic activity in DNA for days at a time

If you want to keep track of someone’s activities for a day, contact them every 10 minutes and inquire what they are up to. It would be simpler, though, to equip them with a journal in which to record their own acts.

1 Aug 2022

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

Rady Children’s Institute for Genomic Medicine (RCIGM®) recently announced the publication in Nature Communications of research that describes and examines the efficiency of Genome-to-Treatment (GTRxTM), a computer-controlled, virtual disease management system that combines a quick Whole Genome Sequencing (rWGS®) diagnosis accomplished in 13.5 hours with a custom lab management information system and analysis pipeline.

28 Jul 2022

Scientists determine the contribution of DNA recombinations to genomic diversity in health and disease

Researchers from Japan’s RIKEN Center for Integrative Medical Sciences, working with colleagues from all over the world, found that recombinations of particular genomic sequences, which are reproduced millions of times in the genome of each human cell, are common in both normal and disease states.

28 Jul 2022