Genomic News and Research

RSS

New toolkit enables researchers to map an individual’s RNA data to a much richer reference

Examining the gene expression of a person needs mapping the RNA landscape to a standard reference. This is done to gain an understanding of the degree to which genes are “turned on” and execute the functions in the body.

From University of California Santa Cruz 18 Jan 2023

Insights into the role of the germline in de novo mutation

The male reproductive system is a hotspot for the introduction of new genes. Perhaps that might assist in understanding why fathers tend to pass on more new mutations than mothers do. However, it does not explain why older fathers pass on more mutations than younger fathers.

16 Jan 2023

Ten years and 1,000 studies later, epigeneticists discover problems in their arsenal

Twenty years ago, following the initial sequencing of the human genome, geneticists started carrying out extensive genome-wide association studies to find genomic regions connected to human disease.

16 Jan 2023

Quicker and affordable method of extracting DNA from elephant dung

With the aid of a novel DNA-collection technique, researchers can now collect genetic data from elephants without endangering the animals or endangering themselves.

16 Jan 2023

Key genes driving cleft lip and palate identified

A research group headed by the University of Iowa recognized three genes that, when deleted, produce cleft lip or palate, a facial abnormality that affects around one in every 1,600 babies in the United States, according to the US Centers for Disease Control and Prevention.

13 Jan 2023

Scandinavian gene pool development via DNA analysis

The complex relationships between geography, ancestry, and gene flow in Scandinavia are resolved in a new study based on 297 ancient Scandinavian genomes that were analyzed along with the genomic data of 16,638 modern Scandinavians.

6 Jan 2023

Uncovering new function for small RNAs in Salmonella infections

Millions of people get sick from Salmonella each year because they are food-borne pathogens. These bacteria rely on a sophisticated network of genes and gene products that give them the ability to sense environmental conditions to do this.

4 Jan 2023

VUMC’s BioVU achieves deep-freeze storage of more than 300,000 biological samples

BioVU, Vanderbilt University Medical Center's biobank, has reached another milestone -; deep-freeze storage of more than 300,000 biological samples.

20 Dec 2022

Genetic cause behind novel DEE syndrome discovered

Autism and epilepsy are two highly prevalent conditions that fall under the umbrella of neurodevelopmental disorders (NDD), which affect 1–3% of the world’s population just in terms of cognitive disabilities.

20 Dec 2022

Analyzing progenitor fate and dynamics long after embryonic development

According to Johns Hopkins Medicine researchers, they have devised a computer model called quantitative fate mapping that looks back in time to track the origin of cells in a fully grown organism.

14 Dec 2022

Preventing protein-protein interactions with a new tool

Proteins constantly interact with one another inside cells to perform various tasks. Blocking the binding of two or more proteins appears as a potential treatment for some diseases where these functions are altered.

1 Dec 2022

Research could advance our understanding of evolution and the origins of cell motility

The origin of all biological movements, including walking, swimming, or flying, can be traced back to cellular movements; however, little is known about how cell motility arose in evolution.

1 Dec 2022

Revealing the mechanism that ensures genome stability in normal cells

To create new cells, the old cells must divide. This is a constant, frequent, and pervasive process that begins with conception and culminates with death.

30 Nov 2022

Importance of localizing BRCA gene mutations for ovarian cancer treatment

Mutations in the BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 persons, respectively, elevate the risk of various malignancies such as ovarian, breast, pancreatic, and prostate cancer considerably.

30 Nov 2022

Newly developed tool helps snip out faulty genes in a safe manner

Scientists from the Massachusetts Institute of Technology (MIT) have come up with a new tool that has the potential to detach faulty genes and exchange them with new ones in a highly safe and effective way.

From Massachusetts Institute of Technology (MIT) 25 Nov 2022

Fastest-evolved regions of the human genome diverged rapidly after split from chimpanzee ancestor

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

New effort to generate high quality reference genomes for 1,000 known species of euglenoids

The Euglena International Network (EIN) (https://euglenanetwork.org/), founded in 2020, is a global consortium of hundreds of scientists around the world with the collective goal of supporting euglenoid science through collaborative and integrative omics between academics and industry.

23 Nov 2022

The influence of genes and small molecules on personal disease risk

Each individual has a unique chemical fingerprint. Small molecules in the blood, like fats or sugars, have a significant impact on how the human body responds to stress, which diseases people are predisposed to, and how serious an illness will be.

23 Nov 2022

Revealing the functional significance of DDX41 in great detail

The DDX41 gene encodes the nuclear enzyme DEAD-box-type RNA helicase. Hematopoietic malignancies are caused by DDX41 mutations. However, the mechanism behind the development of this malignancy remains unknown.

21 Nov 2022

New guidelines for genomic consent benefit patients and researchers

How can Canada maximize the benefits of human genomic sequencing to deepen knowledge of disease? For researchers and decision-makers in this expanding field, new guidance published in CMAJ (Canadian Medical Association Journal) establishes the essential components for obtaining patient consent.

16 Nov 2022