Genomic News and Research

RSS

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

A research team from Italy has discovered a pair of microRNA molecules that assist in maintaining a population of cancerous stem cells that fuel the growth of breast cancers and trigger tumor relapse after treatment.

5 Apr 2021

New research aims to take the study of the human genome to the next level

A global consortium of biologists, geneticists, mathematicians, clinicians, and other scientists is all set to elevate the study of the human genome to the next level—developing an exhaustive atlas of genetic variants to improve the understanding, diagnosis, and treatment of disease.

2 Apr 2021

B.1.1.7 variant of SARS-CoV-2 spreading quickly in the United States

The faster-spreading B.1.1.7 variant of SARS-CoV-2 first detected in the United Kingdom, the coronavirus that causes COVID-19, is quickly on its way to becoming the dominant variant of the virus in the United States, according to a study from scientists at Scripps Research and the COVID-19 test maker Helix.

31 Mar 2021

Six novel CRISPR-Cas12a variants expand genome engineering in plants

Yiping Qi continues to create new genome editing and engineering in plants, with the ultimate objective of enhancing the efficiency of food production.

31 Mar 2021

Specific genes play key roles in response to water stress across bioenergy grass species

The Miscanthus genus of grasses, commonly used to add movement and texture to gardens, could quickly become the first choice for biofuel production. A new study shows these grasses can be grown in lower agricultural grade conditions - such as marginal land - due to their remarkable resilience and photosynthetic capacity at low temperatures.

26 Mar 2021

Bacteria residing within tumor cells may boost cancer immunotherapy

Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. In a new study published in Nature, researchers at the Weizmann Institute of Science and their collaborators have discovered that the immune system "sees" these bacteria and shown they can be harnessed to provoke an immune reaction against the tumor.

23 Mar 2021

Low representation of minority groups in genomic databases may impact therapy selection

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

22 Mar 2021

Rare genetic variants contribute to increased risk for lung cancer

In the United States, lung cancer is the main cause of cancer death in both male and female populations.

19 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

Optimized nano-micelles can induce efficient genome editing in mouse brain

A research team has reported that improved nano-micelles can trigger efficient genome editing in the mouse brain.

15 Mar 2021

Study reveals mechanisms behind the activation of MRN complex

Researchers from the Tokyo Institute of Technology have revealed mechanisms behind the stimulation of the MRN complex—the DNA scissors of the cells.

11 Mar 2021

RNA-editing events can reveal the genetic basis of many human diseases

Scientists from CHOP have detected RNA-editing events that affect the expression of genes and the phenotypic manifestation of that specific expression.

10 Mar 2021

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

10 Mar 2021

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

9 Mar 2021