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New vaccine providing protection against future animal-to-human viral diseases may be possible

A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans -; including SARS-CoV-2, the cause of COVID-19 -; may be possible, say Johns Hopkins Medicine researchers, based on findings from their recent study.

17 Feb 2022

TAB1 gene plays a key role in maintaining stem cells during ovule formation in rice plants

Rice has long been a staple food for more than half the global population. The United Nations even declared 2004 the International Year of Rice to raise awareness and encourage action to protect and advance the crop for a rapidly growing population.

7 Feb 2022

Experts identify subgenome asymmetry at translational level in wheat

Polyploidy is a key route for the creation of new species in plants and a significant means of enhancing agronomic traits in crops.

9 Dec 2021

Research findings likely to help better define risk factors in cancer

Scientists took a further step in the exploration of genetic instability, as exhibited in cancer cells.

7 Oct 2021

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Insights on double-strand break repair may provide better understanding of cancer development

The BRCA1 protein known widely for its role in hereditary breast cancer is also a vital part of the cellular system repairing double-stranded DNA breaks.

From Osaka University 16 Jul 2021

Researchers establish efficient genetic engineering platform in Pichia pastoris

Pichia pastoris is a model methylotrophic yeast that can easily realize high-density fermentation.

13 Jul 2021

Carrying out CRISPR/Cas9 in Space

In our latest interview, AZoLifeSciences spoke to a team of researchers about their latest research which involved carrying out CRISPR/Cas9 in Space.

8 Jul 2021

Three-dimensional organization of genome is extremely dynamic during gamete formation

Inside the nuclei of cells, the genome is tightly organized (packaged). This three-dimensional (3D) genome organization is basic because it controls gene expression.

21 May 2021

Exploring the Genetic effects of Chernobyl Radiation

In this interview, AZoLifeSciences speaks to researchers from the National Cancer Institute about their latest research that investigated the genetic effects of Chernobyl radiation.

From National Cancer Institute (NCI) 13 May 2021

New gene editing approach bypasses disease-causing mutations

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

From Penn State University 22 Apr 2021

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

6 Apr 2021

Study reveals mechanisms behind the activation of MRN complex

Researchers from the Tokyo Institute of Technology have revealed mechanisms behind the stimulation of the MRN complex—the DNA scissors of the cells.

11 Mar 2021

Fungal hybridization confers greater adaptive potential in Verticillium longisporum

Several plant pathogens belong to the genus Verticillium and affect many different plant hosts.

24 Feb 2021

Researchers identify tumor suppressor gene involved in stress response

Even the larvae of the Drosophila fly contain adult progenitor cells. And these cells are the only ones that are preserved throughout the growth and are responsible for the development of adult tissues and organs.

11 Feb 2021

Researchers gain a deep insight into the evolutionary history of bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients. These include receptors for bitter compounds, which first evolved during evolution in bony fishes such as the coelacanth.

3 Feb 2021

Study uncovers unusual sex chromosomes of Australian iconic animals

The sex chromosomes genetically define the developmental fate of an embryo to become a male or a female individual, and usually, appear as one pair of morphologically different chromosomes between sexes.

8 Jan 2021

Study may lead to new treatments for certain types of disease

Researchers at the Francis Crick Institute have found a new way to prevent some tumours from repairing their own DNA, a function that is essential for cancer cell survival. This discovery could lead to much needed new treatments for certain types of the disease.

17 Dec 2020

Imperfect egg cells more common than originally thought

AZoLifeSciences speaks to Dr. Terry Hasssold about his latest research into oocytes and how imperfect egg cells are more common than scientists initially thought.

16 Dec 2020

Scientists identify biosynthetic genes involved in the production of usnic acid in lichens

Scientists from the Faculty of Pharmacy at the Complutense University of Madrid have headed an international study that has successfully detected a sequence of biosynthetic genes that play a key role in the synthesis of usnic acid in lichen—a kind of compound that exhibits antioxidant, antiviral, antibacterial, anticancer, and neuroprotective activity.

14 Dec 2020