Homologous News and Research

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Repair proteins can help healthy cells to avoid damage during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

10 Dec 2020

New method could help resolve unwanted genetic changes associated with CRISPR-Cas9 technique

A research team has used a novel method that could help resolve the issue of unnecessary genetic changes encountered in the CRISPR-Cas9 technique.

7 Dec 2020

Study reveals cellular and molecular mechanisms of hypoxic stress and inflammation

Ion channels, transports, and membrane receptors are immediately delivered to defined cellular membranes once they are synthesized in the cytoplasm.

24 Aug 2020

New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

DNA repair tool is tailored to deal with specific type of complex break, study shows

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Study sheds light on DNA sculpting properties of enigmatic protein

Sometimes, when something is broken, the first step to fixing it is to break it even more. In a recent example, scientists seeking to understand the mechanism of a DNA-repairing enzyme have discovered that the molecule performs its functions by first marking and then further breaking damaged DNA.

22 Jun 2020

New insights into recombination of sex chromosomes during meiosis

As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life.

29 May 2020

Study identifies brain structure that controls our behavior

For our social life and our profession we must be able to deal with our environment and other people. Executive functions, meaning the basic intellectual abilities that control human thought and action, help us to do this.

20 May 2020

Choosing alternate pathways of DNA repair to limit harmful chromosomal rearrangements

Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism.

From Osaka University 30 Apr 2020

NMR spectroscopy reveals mechanisms involved in DNA repair

The information contained in DNA is crucial for life. Hence, the integrity of the DNA has to be maintained extremely well.

27 Apr 2020

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

Study reveals key mechanism behind DNA repair processes

According to a study recently published in the eLife journal, researchers have demonstrated a crucial mechanism involved in the repair processes of DNA double-strand breaks.

25 Mar 2020