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New drug delivery strategy could make it easier for patients to take their medications

In recent years, scientists have developed monoclonal antibodies -; proteins that mimic the body's own immune defenses -; that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn's disease.

31 Aug 2021

Old habit-controlling neurons may also play a key role in learning new tricks

Imagine working on your computer and typing the same long password you have used for years to access your email.

26 Aug 2021

Study identifies C9orf72 repeat expansion using novel genetic marker

Research offers a new genetic tool to pinpoint C9orf72 repeat expansion-carrying frontotemporal lobar degeneration from huge population-based cohorts.

25 Aug 2021

Accurate diagnosis of bacterial superinfection pneumonia could help avoid antibiotic overuse

Only 21 percent of patients with severe pneumonia caused by SARS-CoV-2 (the virus that causes COVID-19) have a documented bacterial superinfection at the time of intubation, resulting in potential overuse of antibiotics, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

23 Aug 2021

Study uncovers mechanism behind skin cell transformation

Researchers have created a recipe for turning skin cells into primitive muscle-like cells that can be sustained indefinitely in the laboratory.

23 Aug 2021

Research reveals Alzheimer’s protein accumulates inside nerve cells

Experimental research has shown that amyloid-beta, the Alzheimer’s protein, accumulates within nerve cells.

23 Aug 2021

Newly developed premature cells can support early heart development

A research group led by Massachusetts General Hospital has developed premature cells that promote early heart development but disappear soon after birth.

23 Aug 2021

Study reveals the biology and treatment behind rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

20 Aug 2021

Study reveals how two separate DNA changes may predict aggressive childhood leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination.

From The University of Utah 20 Aug 2021

New CRISPR-based technique for rapid screening of hundreds of genes in a single experiment

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

From The University of Utah 20 Aug 2021

Researchers modify CRISPR to enable antibody-based medical diagnostics

Researchers adapted CRISPR to analyze antibodies in patient blood samples to pave the way for a new class of medical diagnostics.

From Harvard Medical School 16 Aug 2021

Study uncovers key factors immune cells need to survive in the battle against cancer

A study headed by scientists at Massachusetts General Hospital unravels certain crucial factors required for the survival of immune cells in the fight against cancer.

12 Aug 2021

Research provides a detailed 'proteogenomic' view of lung squamous cell carcinoma

Lung cancer remains the leading cause of cancer-associated death in the United States and worldwide. Patients with a subtype called lung adenocarcinoma (LUAD) have benefited from the development of new targeted medicines, but the search for effective new therapies for another subtype called lung squamous cell carcinoma (LSCC) has largely come up short.

6 Aug 2021

New microscopy method to observe the movement of fast biological processes in 3D

Scientists have come up with a method that enables the use of multi-focal images to reconstruct the movement of fast biological processes in 3D.

29 Jul 2021

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord.

28 Jul 2021

New formulation to administer antibodies for choroidal neovascularization therapy

Scientists have created a new formulation based on regulatory T-cell exosomes (rEXS) to administer vascular endothelial growth factor (VEGF) antibodies.

28 Jul 2021

ACMG and Elsevier announce new partnership to publish 'Genetics in Medicine'

The American College of Medical Genetics and Genomics, the only nationally recognized US medical professional organization solely dedicated to improving health through the practice of medical genetics and genomics, and Elsevier, a global leader in research publishing and information analytics, are delighted to announce a new partnership to publish ACMG's official journal, Genetics in Medicine.

27 Jul 2021

Researchers develop repository showcasing antibody activity on spike protein variants

Scientists have created an “atlas” that charts how 152 different antibodies attack a major piece of the SARS-CoV-2 machinery, the spike protein.

27 Jul 2021

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.

23 Jul 2021

Hospital News and Research

New drug delivery strategy could make it easier for patients to take their medications

Old habit-controlling neurons may also play a key role in learning new tricks

Study identifies C9orf72 repeat expansion using novel genetic marker

Accurate diagnosis of bacterial superinfection pneumonia could help avoid antibiotic overuse

Study uncovers mechanism behind skin cell transformation

Research reveals Alzheimer’s protein accumulates inside nerve cells

Newly developed premature cells can support early heart development

Study reveals the biology and treatment behind rare rheumatoid-like autoinflammatory condition

Study reveals how two separate DNA changes may predict aggressive childhood leukemias

New CRISPR-based technique for rapid screening of hundreds of genes in a single experiment

Researchers modify CRISPR to enable antibody-based medical diagnostics

Study uncovers key factors immune cells need to survive in the battle against cancer

Research provides a detailed 'proteogenomic' view of lung squamous cell carcinoma

New microscopy method to observe the movement of fast biological processes in 3D

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

New formulation to administer antibodies for choroidal neovascularization therapy

ACMG and Elsevier announce new partnership to publish 'Genetics in Medicine'

Researchers develop repository showcasing antibody activity on spike protein variants

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

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