Inflammation News and Research

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Microglia regulate the intrinsic excitability of neuronal subtypes differently

A new study reports that immune cell responses to bacteria affect the intrinsic excitability of rat neuronal subtypes differently.

20 Apr 2022

Double-stranded RNA provoke bone loss during periodontitis

Researchers from Tokyo University of Agriculture and Technology have made a novel revelation about the processes of bone loss in gum disease (periodontitis).

19 Apr 2022

Research associates depressive diseases and deformability of blood cells

For the first time, a study conducted by the TU Dresden and the University of Zurich in collaboration with the Max Planck Institute for the Science of Light finds a relationship between depressive disorders and mechanical features of all main blood cell types.

19 Apr 2022

Discovery could help break the cycle of rapid transmission of TB

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

Researchers introduce injectable stem cell assembly, likely to serve as the treatment for cartilage regeneration

Professor Qiuyu Zhang (Northwestern Polytechnical University), Professor Ki-Bum Lee (Rutgers University), and Professor Liang Kong (School of Stomatology, The Fourth Military Medical University) directed this research.

18 Apr 2022

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

A team of researchers at Sweden’s Karolinska Institutet studied how specific immune cells known as innate lymphoid cells (ILCs), which play a role in inflammatory bowel disease (IBD), evolve into mature cells.

18 Apr 2022

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

According to Weill Cornell Medicine researchers, inhibiting a critical signaling route in brain-resident immune cells may reduce brain inflammation and hence halt the progression of the disease in Alzheimer’s and other neurodegenerative disorders.

15 Apr 2022

Gut viruses contribute to human health, but provoke inflammation when perturbed

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

11 Apr 2022

Understanding the role of ORF8 viral gene in COVID-19 infection and outcomes

A research team led by Jae Jung, PhD, Director of Cleveland Clinic's Global Center for Pathogen & Human Health Research, has uncovered the critical role a viral gene, ORF8, plays in infection and disease outcomes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.

8 Apr 2022

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

A recently discovered chemical compound helped elderly mice with obesity lose fat and weight, add muscle and strength, reduce age-related inflammation and increase physical activity, a new study shows.

7 Apr 2022

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why.

6 Apr 2022

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Researchers have identified a family of proteins that is significantly elevated in the saliva of patients hospitalized with COVID-19.

5 Apr 2022

Checkpoint immunotherapy acts as an interface between killer T cells and dendritic cells

Chronic viral infections and cancers can damage the immune system permanently, diminishing the ability of immune killer T cells to destroy tumor cells or virus-infected cells—a condition known as “immune exhaustion.”

5 Apr 2022

Researchers discover new type of cell that may play a key role in human lung diseases

A new type of cell that resides deep within human lungs and may play a key role in human lung diseases has been discovered by researchers at the Perelman School of Medicine at the University of Pennsylvania.

4 Apr 2022

Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

When a condition is connected to a genetic mutation, it is generally negative news.

4 Apr 2022

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease.

29 Mar 2022

Study reveals genetically driven mucus pathobiology in asthma

A significant amount of genetic risk for asthma is likely mediated through altered gene expression within the airway epithelium.

29 Mar 2022

Study reveals why infected individuals cannot get rid of HIV altogether

Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system.

28 Mar 2022

Scientists create powerful new method for generating protein drugs

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

28 Mar 2022

Hybrid immunity generates improved cell response to fight SARS-CoV-2 infections

People who were infected with SARS-CoV-2 before being vaccinated generate an immune response more specific to fighting viral infections, and produce a broader antibody response, than do people whose only protection is the vaccine, according to researchers at the University of Washington School of Medicine.

25 Mar 2022

Inflammation News and Research

Microglia regulate the intrinsic excitability of neuronal subtypes differently

Double-stranded RNA provoke bone loss during periodontitis

Research associates depressive diseases and deformability of blood cells

Discovery could help break the cycle of rapid transmission of TB

Researchers introduce injectable stem cell assembly, likely to serve as the treatment for cartilage regeneration

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

Gut viruses contribute to human health, but provoke inflammation when perturbed

Understanding the role of ORF8 viral gene in COVID-19 infection and outcomes

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Checkpoint immunotherapy acts as an interface between killer T cells and dendritic cells

Researchers discover new type of cell that may play a key role in human lung diseases

Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Study reveals genetically driven mucus pathobiology in asthma

Study reveals why infected individuals cannot get rid of HIV altogether

Scientists create powerful new method for generating protein drugs

Hybrid immunity generates improved cell response to fight SARS-CoV-2 infections

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