Inflammation News and Research

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Targeting DEL-1 molecule could be an effective way to treat autoimmune disease

Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting as "brakes" on the immune response so it doesn't go overboard.

27 Oct 2020

Researchers develop "mini lungs" to study SARS-CoV-2 infection

'Mini-lungs' grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs.

23 Oct 2020

Study shows antibody-based drug could reduce cancer in mice

Despite the remarkable successes of immune-based treatments for cancer, not everyone responds to these approaches and relapses do occur.

22 Oct 2020

Researchers identify how melanoma redirects the immune system in cancer immunotherapy

The evolution of the refined human immune system has turned into an effective defense system against several diseases, including cancer.

21 Oct 2020

SARS-CoV-2 may induce long-term autoimmune disorder due to self-glycan antibody production

A new study indicated that many of the unusual symptoms of SARS-CoV-2 infections may be due to induced autoimmune responses.

20 Oct 2020

New tool can provide non-invasive decision support for treating lung cancer

Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related death worldwide, two major treatment strategies have emerged: tyrosine kinase inhibitors and immune checkpoint inhibitors.

19 Oct 2020

Small RNA molecule regulates the virulence factors of stomach bacteria

Over 50% of the global population carries the bacterium Helicobacter pylori in their stomach mucosa.

19 Oct 2020

Peptide therapy prevents overreaction of the immune system against infections

Individuals require enough action to remove offensive viruses or bacteria, but not so much that their body suffer a considerable damage.

From UC San Diego 15 Oct 2020

Statins can reduce risk of heart attacks and other cardiovascular diseases

According to a study recently published in the eLife journal, cholesterol-lowering drugs, known as statins, may lower cancer risk in humans via a pathway unassociated with cholesterol.

15 Oct 2020

Researchers unravel molecular factors that drive severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

14 Oct 2020

Severe cases of COVID-19 resemble systemic lupus erythematosus

Scientists from Emory Health Sciences have been observing an intense stimulation of immune cells in severe cases of COVID-19 disease. This activation of immune cells is similar to acute flares of systemic lupus erythematosus (SLE)—an autoimmune disease.

13 Oct 2020

Bone destruction caused by too little sugar

Bone marrow cancer is currently an incurable disease that affects about 400 people in Norway every year. Professor Therese Standal at NTNU has now found an important reason for bone destruction in people with this disease.

12 Oct 2020

Newly developed biodegradable microneedles deliver genes into the skin

Gene therapy offers an excellent potential for treating specific types of genetic defects and cancer, immunological diseases, infections, and wounds.

9 Oct 2020

Immunomodulatory and antioxidant feed additives can reduce effects of coccidiosis

Broiler chicken producers the world over are all too familiar with coccidiosis, a parasite-borne intestinal disease that stalls growth and winnows flocks.

8 Oct 2020

Urban air pollution may make COVID-19 more severe for some

In a recent study, researchers at Emory University found that long-term exposure to urban air pollution may have made COVID-19 more deadly.

8 Oct 2020

Microneedles For Therapeutic Gene Delivery

There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections.

7 Oct 2020

MIT engineers develop a method to turn off specific genes in bone marrow cells

Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells.

From Massachusetts Institute of Technology (MIT) 6 Oct 2020

Researchers identify a promising treatment for COVID-19 infection

An effective method for treating the 2003 SARS epidemic, also works on the closely associated SARS-CoV-2 virus.

5 Oct 2020

Understanding beta-cell growth mechanisms may help treat metabolic diseases

New treatments for metabolic diseases, such as type 2 diabetes, could emerge from a study of how a single enzyme controls the growth of the pancreatic cells that produce insulin.

5 Oct 2020

Researchers map genetic networks controlling human regulatory T cell identity

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

5 Oct 2020