Intensive Care News and Research

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SARS-CoV-2 virus does not spread on hospital surfaces

By observing what was going on across the world in early 2020, researchers from the University of California San Diego School of Medicine knew that their region will soon be flooded with patients infected with COVID-19—the disease caused by the coronavirus, SARS-CoV-2.

From UC San Diego 11 Jun 2021

Cell adaptation to adverse conditions could differentiate survivors and non-survivors of critical illness

Creating the best conditions for cells to make energy and survive critical illness is a challenge little understood in modern medicine.

27 Apr 2021

New label-free immune profiling assay to assess rapidly changing host immune response

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a new label-free immune profiling assay that profiles the rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves, which can often be at low levels within a host.

26 Mar 2021

Genomics study examines the impact of COVID-19 on care homes

Care homes are at high risk of experiencing outbreaks of COVID-19, the disease caused by SARS-CoV-2. Older people and those affected by heart disease, respiratory disease and type 2 diabetes - all of which increase with age - are at greatest risk of severe disease and even death, making the care home population especially vulnerable.

4 Mar 2021

Study reveals a major genetic risk factor for severe COVID-19

In 2020, a research team demonstrated that a significant genetic risk factor for severe COVID-19 infection was inherited from Neanderthals.

17 Feb 2021

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease.

12 Feb 2021

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

According to a new study, non-steroidal anti-inflammatory drugs (NSAIDs) decreased both inflammatory and antibody responses to SARS-CoV-2 infection in mice.

26 Jan 2021

Augmented response of immune system explains COVID-19 severity in patients with hypertension

COVID-19 patients who also suffer from high blood pressure are more likely to fall severely ill with the disease, which also leaves them at greater risk of death.

12 Jan 2021

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

CAR T cells are a breakthrough class of effective but often toxic cancer therapies. To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug.

7 Jan 2021

Interleukin 10 levels could warn about the progression of COVID-19

Immunology experts have collaborated to use their groundbreaking research techniques to put people’s response to COVID-19 disease under the microscope.

16 Nov 2020

Study shows sleep apnea may be a risk factor for COVID-19

The question of sleep apnea as the risk factor for COVID-19 arose in a study conducted by the Turku University Hospital and the University of Turku on patients of the first wave of the pandemic.

16 Nov 2020

Scientists develop novel lab testing procedure for detection of SARS-CoV-2 antibodies

Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn't tell you everything about your immunity.

20 Oct 2020

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

SARS-CoV-2 continues to cause an ongoing pandemic as of October 2020, with over 35 million reported cases and over 1 million deaths around the world.

13 Oct 2020

Severe cases of COVID-19 resemble systemic lupus erythematosus

Scientists from Emory Health Sciences have been observing an intense stimulation of immune cells in severe cases of COVID-19 disease. This activation of immune cells is similar to acute flares of systemic lupus erythematosus (SLE)—an autoimmune disease.

13 Oct 2020

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

Study highlights the effects of antibiotics on breast milk microbiota milk

A team led by researchers at the University of Toronto and The Hospital for Sick Children has found that mothers of preterm babies have highly individual breast milk microbiomes, and that even short courses of antibiotics have prolonged effects on the diversity and abundance of microbes in their milk

From University of Toronto 4 Sep 2020

Intensive Care News and Research

SARS-CoV-2 virus does not spread on hospital surfaces

Cell adaptation to adverse conditions could differentiate survivors and non-survivors of critical illness

New label-free immune profiling assay to assess rapidly changing host immune response

Genomics study examines the impact of COVID-19 on care homes

Study reveals a major genetic risk factor for severe COVID-19

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

Augmented response of immune system explains COVID-19 severity in patients with hypertension

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

Interleukin 10 levels could warn about the progression of COVID-19

Study shows sleep apnea may be a risk factor for COVID-19

Scientists develop novel lab testing procedure for detection of SARS-CoV-2 antibodies

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

Severe cases of COVID-19 resemble systemic lupus erythematosus

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Study highlights the effects of antibiotics on breast milk microbiota milk

Research identifies TLR7 gene that predisposes individuals to severe COVID-19

AI can be used as a supplementary tool for identifying causal pathogens of pneumonia

New approach is more effective in treating certain blood cancers

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

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