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Two cryo-EM studies identify different types of ATP synthase organization

The mitochondrial ATP synthase is energy-converting macromolecular machine that uses the electrochemical potential across the bioenergetic membrane called cristae. This potential is maintained via a membrane curvature that is induced by ATP synthase assembled in dimers.

11 Jan 2021

Researchers discover new way to control natural killer cells in immune system

UC San Francisco scientists have discovered a new way to control the immune system's "natural killer" (NK) cells, a finding with implications for novel cell therapies and tissue implants that can evade immune rejection.

11 Jan 2021

Sequencing-based solution can help determine patients’ response to infection therapy

Scientists from the University of Helsinki have created a new sequencing-based strategy for identifying pathogens from complex samples.

8 Jan 2021

Novel treatments could cut the death rate from dengue, Zika, West Nile viruses

A new study led by researchers from The University of Queensland (UQ) could help identify new therapies to reduce the global death rate caused by Zika, West Nile, and dengue viruses.

8 Jan 2021

$Loss of enzymatic processes can increase the risk of bone fracture$

Loss of enzymatic processes can increase the risk of bone fracture

When enzymatic processes decline inside the body, they can increase the risk of bone fracture in a person.

8 Jan 2021

New class of protein materials can influence cell signaling

A new study has revealed that a novel class of protein material that communicates with living cells without being absorbed by them can affect cell signaling. The protein material does this by attaching and sequestering cell surface receptors.

7 Jan 2021

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

CAR T cells are a breakthrough class of effective but often toxic cancer therapies. To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug.

7 Jan 2021

Scientists discover why food-ingredient-based pesticide is effective against spider mites

Scientists have uncovered why a food-ingredient-based pesticide made from safflower and cottonseed oils is effective against two-spotted spider mites that attack over a thousand species of plants while sparing the mites' natural predators.

7 Jan 2021

DNA-editing technique used to extend lifespan of mice with progeria

Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life expectancy.

From National Human Genome Research Institute (NHGRI) 7 Jan 2021

Microbe found in the colon may promote breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

7 Jan 2021

New technological development could revolutionize the dairy industry

Might a new technological development of researchers from Tel Aviv University soon revolutionize the dairy products we consume?

7 Jan 2021

Longitudinal study identifies many genetic markers linked to bone mineral accrual

A multidisciplinary team of researchers led by Children's Hospital of Philadelphia has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

7 Jan 2021

Sugar-binding protein could serve as a useful biomarker for patients at risk of sepsis

According to a research team headed by the University of Connecticut Health, a sugar-binding protein could drive terrible inflammation and worsen sepsis—a disease that kills over 270,000 individuals per year in the United States alone.

5 Jan 2021

New study uncovers how grasslands used by humans change our climate

Grasslands are managed worldwide to support livestock production, while remaining natural or semi-natural ones provide critical services that contribute to the wellbeing of both people and the planet.

5 Jan 2021

Altered sugar composition impacts cell-to-surface adhesion

Biotechnologists measure the forces with which algae cells adhere to surfaces and move on them. How can cells adhere to surfaces and move on them? This is a question that was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China).

4 Jan 2021

Gut cells raise alarm during parasite invasion

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder.

29 Dec 2020

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.

29 Dec 2020

A protein encourages cell stickiness during development

Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development.

28 Dec 2020

Scientists discover new class of compounds for combating antimicrobial resistance

Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature.

24 Dec 2020

Genomic study of weedy seadragons reveals significantly distinct populations

Charismatic, iconic and Instagram-friendly, the weedy seadragon is a favourite with divers and snorkellers. The first genomic study of east coast Australian seadragon populations can now reveal "weedies" from NSW, Victoria and Tasmania are significantly different.

24 Dec 2020