Leukemia News and Research

RSS

Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.

Attacking a protein in prostate cancer cells stops the disease spread, research finds

Cedars-Sinai scientists discovered that attacking a protein present in prostate cancer cells could stop the disease from further spreading to various other parts of the body.

2 Mar 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

A group of researchers from UNIGE in Switzerland and Inserm in France has discovered a previously unknown process that could lead to the creation of novel medicines.

18 Feb 2022

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops.

8 Feb 2022

San Antonio researchers report a new mechanistic target for leukemia drug development

Scientists at The University of Texas Health Science Center at San Antonio believe it may be possible to prevent DNA changes driven by two proteins highly active in leukemia and other cancers.

7 Feb 2022

RNA sequencing picks up more genetic changes in pediatric cancer patients than traditional tests

Analysis of the entire tumor RNA picks up more clinically relevant genetic changes in children with cancer than traditional diagnostic methods, new research has shown.

28 Jan 2022

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.

From Society for Laboratory Automation and Screening (SLAS) 27 Jan 2022

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Acute myeloid leukemia (AML) is an aggressive cancer of white blood cells with few effective targeted therapies available to treat it.

12 Jan 2022

Fingerprints are influenced by the limb development genes, says study

Researchers found that the shape of fingerprints is determined by limb development genes instead of skin patterning genes, in the most thorough analysis to date.

10 Jan 2022

Biochemical signals sent from cell to cell play a key role in deciding their fate

Scientists have found a way to prove that biochemical signals sent from cell to cell play an important role in determining how those cells develop.

24 Dec 2021

Study identifies novel function for existing protein

Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).

23 Dec 2021

Study targets metabolic pathways to identify sensitivities among cancer cells

Metabolic reprogramming, accepted as a hallmark of cancer, might indicate a vulnerability to be used by targeted cancer therapy.

17 Dec 2021

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

In the late 1980s, scientists developed a revolutionary approach to treating acute myeloid leukemia (AML), a type of blood cancer. Called differentiation therapy, it amounted to a bona fide cure for many patients.

2 Dec 2021

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

Study unearths novel mechanism coordinating the assembly of cell components

A group of researchers recently unearthed vital information on how gene expression is orchestrated.

2 Dec 2021

UD biochemist explores how mRNA eraser enzymes work in our cells

University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how science can pave the way for possible solutions to this problem.

25 Nov 2021

Research findings anticipated to facilitate production of novel drug candidates

Pharmaceuticals commonly available on the market are developed by linking together rings of molecules to generate drugs that treat conditions like depression.

19 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Cellular enlargement drives a decline in function of stem cells, study suggests

MIT biologists have answered an important biological question: Why do cells control their size? Cells of the same type are strikingly uniform in size, while cell size differs between different cell types. This raises the question of whether cell size is important for cellular physiology.

15 Nov 2021

Using a new genetic technology to decipher intratumoral heterogeneity

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

12 Nov 2021

Leukemia News and Research

Attacking a protein in prostate cancer cells stops the disease spread, research finds

Looking at protein activity gives a complete picture of leukemia's weaknesses

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

San Antonio researchers report a new mechanistic target for leukemia drug development

RNA sequencing picks up more genetic changes in pediatric cancer patients than traditional tests

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Fingerprints are influenced by the limb development genes, says study

Biochemical signals sent from cell to cell play a key role in deciding their fate

Study identifies novel function for existing protein

Study targets metabolic pathways to identify sensitivities among cancer cells

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

Study unearths novel mechanism coordinating the assembly of cell components

UD biochemist explores how mRNA eraser enzymes work in our cells

Research findings anticipated to facilitate production of novel drug candidates

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Cellular enlargement drives a decline in function of stem cells, study suggests

Using a new genetic technology to decipher intratumoral heterogeneity

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

Latest in Genomics