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Researchers identify specific genes that cause schizophrenia

A substantial number of individual genes that potentially play essential roles in schizophrenia have been uncovered in the largest-ever genomic analysis of the psychiatric condition.

11 Apr 2022

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

In new research, UT Southwestern scientists report that imaging a key immunity protein known as STING at near-atomic resolution reveals a previously undiscovered binding location that appears to be crucial for launching immunological attacks.

11 Apr 2022

Researchers discover how an “accordion effect” is vital for switching off genes

In a study that changes the fundamentals of what researchers know about gene silencing, WEHI researchers demonstrated how an “accordion effect” is key to switching off genes.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Apr 2022

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why.

6 Apr 2022

Study reveals genetically driven mucus pathobiology in asthma

A significant amount of genetic risk for asthma is likely mediated through altered gene expression within the airway epithelium.

29 Mar 2022

Minuscule involuntary eye movements are not drivers of brain signals underlying attention

Minuscule involuntary eye movements, known as microsaccades, can occur even while one is carefully staring at a fixed point in space.

28 Mar 2022

Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

NIH’s research program publishes genomic information of nearly 100,000 individuals

The National Institutes of Health’s All of Us Research Program currently has access to about 100,000 extremely varied whole genome sequences.

21 Mar 2022

Inclusive new tool for genomic research boosts efforts to develop more precise treatments for diseases

Scientists have developed a powerful, inclusive new tool for genomic research that boosts efforts to develop more precise treatments for many diseases by leveraging a better representation of the genetic diversity of people around the world.

11 Mar 2022

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

8 Mar 2022

Novel DNA test helps diagnose neurological and neuromuscular genetic diseases

The Garvan Institute of Medical Research came up with a new DNA test that helps determine a range of hard-to-diagnose neurological diseases faster.

7 Mar 2022

Several variants of COVID-19 may hide away from body’s immune system, new study reveals

A recent study published in Nature Communications by an international research group suggests that people infected with COVID-19 may have several distinct SARS-CoV-2 variants stashed away from the immune system in various parts of the body.

3 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

New computational tool simulates evolution

The building blocks of life-saving therapeutics could be developed in days instead of years thanks to new software that simulates evolution.

25 Feb 2022

Scientists develop a new approach to study Sars-CoV-2

Scientists at the Max Planck Institute for Medical Research in Heidelberg and their collaborators at the Max Planck Bristol Center for Minimal Biology at the University of Bristol have developed a new approach to study Sars-CoV-2.

From The Max Planck Institute 23 Feb 2022

3D structure of protein channel helps shed light on sensitive touch response of Venus fly traps

Scientists at Scripps Research have revealed the three-dimensional structure of Flycatcher1, an aptly named protein channel that may enable Venus fly trap plants to snap shut in response to prey.

18 Feb 2022

Researchers discover DisCo for effective processing of samples with fewer cells

Single-cell RNA sequencing is an approach that lets researchers to study the gene expression in an individual cell within a mixed population.

16 Feb 2022

Gene-editing techniques could be used to tackle mitochondrial disorders, study shows

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

9 Feb 2022

Genetic insights offer potential new targets for acne treatment

A study of the genetics of acne has identified 29 regions of the genome that influence the condition. These genetic insights offer potential new targets for treatment. They may also help clinicians identify individuals at high risk of severe disease.

8 Feb 2022

New method helps distinguish bacterial DNA from human and other non-bacterial cells

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

4 Feb 2022