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Two-step screening of aroma compounds reveals a novel and effective modulator of dendritic cells

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

13 Feb 2023

A treatment strategy to hasten cancer cell death

Gene mutations are the cause of cancer. Tumor suppressors and oncogenes are the two main groups of these altered genes in cancer. Mutations in oncogenes can drive cell proliferation, pushing the gas pedal to the floor, whereas mutations in tumor suppressor genes can cause tumors to grow unchecked—a situation in which there is no control.

13 Feb 2023

Rare disease involving speech and motor coordination difficulties identified

Scientists from the National Institutes of Health recently identified a new neurological condition characterized by issues with motor coordination and speech. Their observations were published in the journal npj Genomic Medicine.

From National Human Genome Research Institute (NHGRI) 13 Feb 2023

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

Individuals with cocaine use disorder exhibit gene expression changes in two brain regions: the nucleus accumbens, a region associated with reward, and the caudate nucleus, a region mediating habit formation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published February 10 in Science Advances.

13 Feb 2023

The correlation between Type 2 diabetes and human microRNAs

Although it has long been believed that microRNA (miRNA) molecules in pancreatic islets play significant roles in Type 2 diabetes, no specific miRNAs have been definitively linked to the disease in humans.

10 Feb 2023

Prolonged alcohol use and its detrimental effects on blood protein snapshot

Jon Jacobs, a biochemist, has examined the blood of people suffering from diseases including Ebola, cancer, TB, hepatitis, diabetes, Lyme disease, brain damage, and influenza.

10 Feb 2023

Genetic variants that increase the risk of ADHD identified

Why are some people diagnosed with ADHD while others are not? And when is the seed of ADHD sown, in life or the womb?

10 Feb 2023

Importance of epigenetic regulation in the recovery of T cells

In stem cell transplants for leukemia treatment, the patient’s hematopoietic system is removed and replaced with hematopoietic cells from donors.

10 Feb 2023

Specific types of gut fungi play a role in infant weight gain and growth

Researchers in the Cumming School of Medicine (CSM) at the University of Calgary in collaboration with the Canadian CHILD Study have found a link between the diversity, or number, of fungal species in the infant gut and the body-mass index (BMI) of infants.

10 Feb 2023

Researchers pioneer a new approach to study mosquito's DNA

When it comes to DNA, one pesky mosquito turns out to be a rebel among species.

10 Feb 2023

UVA researchers discover a key trigger for common liver disease

University of Virginia School of Medicine researchers have discovered a key trigger for non-alcoholic fatty liver disease, a mysterious condition that causes fat to build up in the liver for no clear reason.

10 Feb 2023

Researchers address new quantitative approaches to better define cancer epigenetic landscape

It is now widely understood that cancer is a disease of acquired defects in genes and gene function.

10 Feb 2023

Large-scale differentiation of iPSC-derived motor neurons from ALS patients

A new Cedars-Sinai study in collaboration with the University of California, Irvine (UCI) and the Answer ALS consortium has examined the expression of thousands of genes in stem cell generated motor neurons that are known to die in patients with amyotrophic lateral sclerosis, a fatal neurological disorder known as ALS or Lou Gehrig's disease.

10 Feb 2023

U.S. people show interest in using genetic technologies to improve offspring education

An article published today in the journal Science indicates that a substantial proportion of Americans are willing to use an essentially unregulated reproductive genetic technology to increase the chances of having a baby who is someday admitted to a top-100 ranked college.

10 Feb 2023

New platform to study the feeding behavior of mosquitoes

If watching animals feast on human blood for 30-plus hours isn't your idea of fun, don't worry. The robot can do it.

10 Feb 2023

Protein-rich droplets in cells linked to many unresolved diseases

Most proteins localize to distinct protein-rich droplets in cells, also known as "cellular condensates". Such proteins contain sequence features that function as address labels, telling the protein which condensate to move into.

9 Feb 2023

Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Notalgia paresthetica-;a nerve disorder characterized by a persistent itch in the upper back-;is a common and underdiagnosed condition worldwide.

9 Feb 2023

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meeting

Complete Genomics Inc., a global life science tools leader and subsidiary of MGI Tech Co., Ltd. (“MGI”), today launched new revolutionary products and prices at Advances in Genome Biology and Technology (AGBT) General Meeting.

From Complete Genomics 9 Feb 2023

New database of genotype-phenotype associations for monogenic cardiovascular diseases

Monogenic cardiovascular disease is a genetic disease in which cardiovascular damage is the only or main phenotype. The total current number of patients worldwide exceeds 10 million.

9 Feb 2023

Strata Oncology publishes study validating integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit

Strata Oncology, Inc., a next-generation precision oncology company enabling smarter and earlier cancer treatment, today announced the publication of a new peer-reviewed study validating the clinical utility of the company's proprietary pan-solid tumor predictive biomarker for anti-PD-1/PD-L1 checkpoint inhibitor monotherapy benefit, Immunotherapy Response Score (IRS).

8 Feb 2023

Medicine News and Research

Two-step screening of aroma compounds reveals a novel and effective modulator of dendritic cells

A treatment strategy to hasten cancer cell death

Rare disease involving speech and motor coordination difficulties identified

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

The correlation between Type 2 diabetes and human microRNAs

Prolonged alcohol use and its detrimental effects on blood protein snapshot

Genetic variants that increase the risk of ADHD identified

Importance of epigenetic regulation in the recovery of T cells

Specific types of gut fungi play a role in infant weight gain and growth

Researchers pioneer a new approach to study mosquito's DNA

UVA researchers discover a key trigger for common liver disease

Researchers address new quantitative approaches to better define cancer epigenetic landscape

Large-scale differentiation of iPSC-derived motor neurons from ALS patients

U.S. people show interest in using genetic technologies to improve offspring education

New platform to study the feeding behavior of mosquitoes

Protein-rich droplets in cells linked to many unresolved diseases

Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meeting

New database of genotype-phenotype associations for monogenic cardiovascular diseases

Strata Oncology publishes study validating integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit

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