Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

Gene therapy protects eye cells in mice with retinitis pigmentosa

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published today in eLife.

15 Apr 2021

Study reveals DNA supercoiling is involved in regulating gene expression

The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information.

15 Apr 2021

Obesity reduces mitochondrial gene expression in fat tissues

A university has recently completed a study that suggests that the machinery responsible for handling the energy in fat tissues is performing poorly in obesity.

12 Apr 2021

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A group of researchers from France, Germany, Belarus, Japan, and Russia and headed by a scientist from Skolkovo Institute of Science and Technology (Skoltech) has discovered how Mycobacterium tuberculosis survives in iron-deficient environments by using rubredoxin B (RubB)—a protein that belongs to the rubredoxin family and plays a significant role in adapting to varying environmental conditions.

9 Apr 2021

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

According to a study, DNA defects in the energy “factories” of a cell increase the chance of survival in patients suffering from bowel cancer.

9 Apr 2021

Researchers upend the models of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

From Vanderbilt University 8 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

A research team from Italy has discovered a pair of microRNA molecules that assist in maintaining a population of cancerous stem cells that fuel the growth of breast cancers and trigger tumor relapse after treatment.

5 Apr 2021

Processed meat associated with an increased risk of cardiovascular disease

Red meat is a major source of medium- and long-chain saturated fatty acids, which may lead to an increased risk of cardiovascular disease. Processed meat, which has been modified to improve taste or extend its shelf-life, has also been associated with an increased risk of cardiovascular disease.

1 Apr 2021

Lowering apolipoprotein CIII levels can prevent deleterious effects of a high-fat diet

Consumption of a diet with high fat levels increases the risk of fatty liver, obesity, cardiovascular diseases, and type 2 diabetes.

15 Mar 2021

ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

Study identifies genes responsible for peach's tolerance to stress

A Boyce Thompson Institute-led team has identified genes enabling peaches and their wild relatives to tolerate stressful conditions -- findings that could help the domesticated peach adapt to climate change.

10 Mar 2021

New technological approach to rapidly develop new drugs without animal experiments

A team of researchers led by Professor Yaakov Nahmias, director of the Grass Center for Bioengineering at the Hebrew University of Jerusalem and founder of Tissue Dynamic, introduced a new technological approach that has the potential to rapidly develop new drugs without the need for animal experiments.

10 Mar 2021

Psychoactive component of marijuana stays in breast milk for up to six weeks, study finds

In a new study published in JAMA Pediatrics, researchers at Children's Hospital Colorado have found that tetrahydrocannabinol (THC), the psychoactive component of marijuana, stays in breast milk for up to six weeks, further supporting the recommendations of the American Academy of Pediatrics, the American College of Obstetricians and Gynecologists and the Academy of Breastfeeding Medicine to abstain from marijuana use during pregnancy and while a mother is breastfeeding.

9 Mar 2021

Gut mycobiome correlates with metabolic outcomes in response to diet

Studies of the microbiome in the human gut focus mainly on bacteria. Other microbes that are also present in the gut -- viruses, protists, archaea and fungi -- have been largely overlooked.

8 Mar 2021

New sensor can rapidly detect RNA and DNA molecules

According to a new study, a tiny sensor used in brain chemistry research can rapidly identify the crucial molecules that offer the genetic instructions for life.

5 Mar 2021

Vegan diet leads to poorer bone health, shows study

The vegan diet is on-trend. How this type of diet affects health is the subject of scientific studies. In a new study from the German Federal Institute for Risk Assessment (BfR), the bone health of 36 vegans, as well as 36 people following a mixed-food diet, was determined with an ultrasound measurement of the heel bone.

5 Mar 2021

New study on plant metabolism can help produce more food for increasing population

A new study has demonstrated how plants exploit their metabolism to identify time and know when to develop.

2 Mar 2021

Novel agonistic effect of polyphenol compound could treat amyloidosis, other metabolic disorders

Reportedly, Curcumin has several physiological activities, which include anti-inflammatory, anti-oxidation, anti-amyloid, and anti-cancer properties.

1 Mar 2021

Metabolism News and Research

Gene therapy protects eye cells in mice with retinitis pigmentosa

Study reveals DNA supercoiling is involved in regulating gene expression

Obesity reduces mitochondrial gene expression in fat tissues

New method can improve the drug testing process

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

Researchers upend the models of cancer metabolism

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Study identifies a pair of microRNA molecules that maintain the population of cancerous stem cells

Processed meat associated with an increased risk of cardiovascular disease

Lowering apolipoprotein CIII levels can prevent deleterious effects of a high-fat diet

ADAR1 protein offers a potential therapeutic target for cancer

Study identifies genes responsible for peach's tolerance to stress

New technological approach to rapidly develop new drugs without animal experiments

Psychoactive component of marijuana stays in breast milk for up to six weeks, study finds

Gut mycobiome correlates with metabolic outcomes in response to diet

New sensor can rapidly detect RNA and DNA molecules

Vegan diet leads to poorer bone health, shows study

New study on plant metabolism can help produce more food for increasing population

Novel agonistic effect of polyphenol compound could treat amyloidosis, other metabolic disorders

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