Metabolites News and Research

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Scientists use gene-editing technique to considerably increase the production of formicamycin antibiotics

Researchers have leveraged gene-editing advances to obtain a 10 times increase in the development of super-bug targeting formicamycin antibiotics.

13 Jan 2021

Metabolites may be predictive indicators for recurrent major depressive disorder

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -- small molecules produced by the process of metabolism -- may be predictive indicators for persons at risk for recurrent major depressive disorder.

13 Jan 2021

Pillar-like molecules could be used as biosensors to detect metabolites

Metabolites are essentially organic molecules that are formed or participate during the biochemical reactions that continuously occur in an organism.

12 Jan 2021

Study: Eating avocado as part of daily diet can help improve gut health

Eating avocado as part of your daily diet can help improve gut health, a new study from University of Illinois shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or "gut."

16 Dec 2020

Molecular markers in the blood can predict severe COVID-19 outcomes

Molecular markers in the blood shown to be predictive of severe COVID-19 outcomes resulting from SARS-CoV-2 coronavirus infection have been identified in a study by a Chinese research team.

15 Dec 2020

New analysis technique could pave way for major breakthroughs in immunotherapy

In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukaemia.

14 Dec 2020

New portable optical sensor can monitor plant stress

The portable device allows rapid detection of nitrogen deficiency - a critical nutrient for plant health. When tested on popular vegetables such as Spinach and Kai-Lan, the device was also able to detect levels of other metabolites; allowing measurement of a wider range of plant stress phenotypes such as drought, heat/cold, saline, and light stress.

11 Dec 2020

Biochemist discovers hidden cellular machinery essential for higher-order life

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.

7 Dec 2020

Disturbances in the gut microbiome may explain major depressive disorder

Researchers have successfully detected three bacteriophages, 50 fecal metabolites, 47 bacterial species that were considerably more or less abundant in patients with major depressive disorder (MDD) when compared to healthy controls. The study involved 311 individuals.

4 Dec 2020

Study may lead to novel organisms that are more efficient at converting plants into biofuels

A new study reveals how bacteria control the chemicals produced from consuming 'food.' The insight could lead to organisms that are more efficient at converting plants into biofuels.

4 Dec 2020

Researchers design living plant-based sensor to track arsenic levels

For the first time, researchers from SMART have engineered a living plant-based sensor for the detection of arsenic in the belowground environment

3 Dec 2020

Chemical compounds in foods can inhibit a key SARS-Cov-2 enzyme

Chemical compounds in foods or beverages like green tea and dark chocolate can bind to and block the function of an enzyme in SARS-CoV-2.

3 Dec 2020

Study reveals metabolic signaling pathways that influence key immune cells

Effector regulatory T cells, also known as eTreg cells, are a specialized subset of white blood cells that maintain the immune system.

18 Nov 2020

Bacterial microbes in the human gut could help diagnose and treat autism spectrum disorder

Every year, 1 out of 54 children in the United States is diagnosed with autism spectrum disorder, and the count has been increasing, reports the Centers for Disease Research.

16 Nov 2020

Study confirms correlation between gut microbiota and Alzheimer's disease

Alzheimer's disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole.

16 Nov 2020

Scientists identify new way to turn energy-poor pathway products into biorenewable ones

The imminent environmental crisis calls for an urgent transition to a green economy. A team of scientists at Nagoya University, Japan, led by Professor Susumu Saito, has recently found an interesting way to make this happen -- by leveraging an important metabolic pathway in living cells.

16 Nov 2020

In-depth review of plant natural products paves way for drug discovery

Scientists have compiled the first comprehensive review of plant natural products that play a role in antibacterial activity, to serve as a guide in the search for new drugs to combat antibiotic-resistant pathogens.

12 Nov 2020

Researchers to explore the role of gut microbes in childhood celiac disease

Boston College Assistant Professor of Biology Emrah Altindis has received a three-year, $300,000-grant from the G. Harold and Leila Y. Mathers Foundation for research into childhood celiac disease.

4 Nov 2020

Different microbial enzymes show promise for practical application

At Kazan Federal University, the Laboratory of Enzyme Biosynthesis and Bioengineering is involved in many projects in applied and fundamental fields of medicine and biology.

2 Nov 2020

Gut microbes mitigate radiation exposure, repair GI tract

A new study by scientists at UNC Lineberger Comprehensive Cancer Center and colleagues published Oct. 30, 2020, in Science, showed that mice exposed to potentially lethal levels of total body radiation were protected from radiation damage if they had specific types of bacteria in their gut.

2 Nov 2020