Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

25 Mar 2021

Specific enzyme can delay the growth and spread of neck and head carcinomas

Scientists were able to considerably delay the growth and proliferation of tumors in mice and improve the effectiveness of immunotherapy.

24 Mar 2021

Study into cellular filopodia could optimize cancer therapy and wound closure

Imagine using only a finger to heal a wound! It seems like science fiction, reminding one of the 1982 movie E.T.

23 Mar 2021

Adhesion strength and contractility enable metastatic cancer cells to display adurotactic behavior

Bioengineers at the University of California San Diego and San Diego State University have discovered a key feature that allows cancer cells to break from typical cell behavior and migrate away from the stiffer tissue in a tumor, shedding light on the process of metastasis and offering possible new targets for cancer therapies.

From UC San Diego 10 Mar 2021

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

9 Mar 2021

New hydrogel shrinks tumors in melanoma mice model

Recently, messenger RNA, also called mRNA, vaccines, to combat the COVID-19 infection have made headlines worldwide, but researchers have already been experimenting with mRNA vaccines to prevent or cure other illnesses, including certain types of cancer.

18 Feb 2021

Research links blood-clotting protein with CNS B-cell lymphoma growth

In people with central nervous system (CNS) lymphoma, cancerous B cells--a type of white blood cell--accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels.

18 Feb 2021

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.

17 Feb 2021

Researchers use mouse models to explain how cancer cells spread

Most tumors consist of a heterogenous mix of cells. Genetic mutations found only in some of these cells are known to aid with the spread and progression of cancer.

15 Feb 2021

Genomic test helps identify prostate cancer patients who may benefit from hormone therapy

A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers.

12 Feb 2021

Researchers discover new molecular mechanism that promotes cell migration

Research groups at the University of Helsinki and Institut Jacques Monod, Paris, discovered a new molecular mechanism that promotes cell migration. The discovery sheds light on the mechanisms that drive the uncontrolled movement of cancer cells and also revises the 'textbook view' of cell migration.

10 Feb 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

Drug-resistant, metastasis-causing cells produce exponentially growing tumors

The cover for issue 1 of Oncotarget features Figure 2, "Results in clinical trials," published in "Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer" by Blagoev, et al. which reported that most metastatic cancers develop drug resistance during treatment and continue to grow, driven by a subpopulation of cancer cells unresponsive to the therapy being administered.

27 Jan 2021

Metastasis News and Research

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Specific enzyme can delay the growth and spread of neck and head carcinomas

Study into cellular filopodia could optimize cancer therapy and wound closure

Adhesion strength and contractility enable metastatic cancer cells to display adurotactic behavior

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

New hydrogel shrinks tumors in melanoma mice model

Research links blood-clotting protein with CNS B-cell lymphoma growth

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Researchers use mouse models to explain how cancer cells spread

Genomic test helps identify prostate cancer patients who may benefit from hormone therapy

Researchers discover new molecular mechanism that promotes cell migration

Unique proteomics-based technology can help diagnose breast cancer more accurately

Drug-resistant, metastasis-causing cells produce exponentially growing tumors

New mathematical model captures forces involved in cell movement

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

Chromosomal instability is associated with cancer's aggressiveness

Researchers detect new immune cells that act as major driver of breast cancer growth

Study elucidates genes responsible for Glioblastoma invasiveness

Study reveals new target to make breast cancer more sensitive to immunotherapy

Biologists unravel how tissue geometry influences cell migration

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