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Research sheds light on innovative techniques to improve drugs for diseases

In a paper that was just published in Science, scientists from Sweden’s Karolinska Institutet and SciLifeLab explain how they were able to enhance a protein’s capacity to repair oxidative DNA damage while also giving the protein a new role.

27 Jun 2022

Researchers discover a way for detecting resistance-encoding genes in bacteria

Chalmers University of Technology researchers have devised a method for detecting certain bacterial genes that encode resistance using conventional microscopes, which are already used to diagnose TB in low-income countries.

27 Jun 2022

Researchers capture a new high-resolution view of the rabies virus

Around 59,000 individuals are shockingly killed by the rabies virus each year, and several of them are children. Some victims, particularly children, discover they have been exposed after it is too late.

20 Jun 2022

Researchers reveal how blood serum impacts the survival and metabolism of bacteria

In hospitals, the Staphylococcus aureus bacteria can be transported from the skin or nasal cavity into open wounds and, possibly, the bloodstream, posing a fatal hazard. Staph infections killed over 20,000 Americans in 2017, according to the Centers for Disease Control and Prevention.

20 Jun 2022

Novel nanoparticle therapeutic shows potential for treating human cancers

Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.

15 Jun 2022

Researchers demonstrate a possible new way of generating insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.

14 Jun 2022

A signaling molecule can make plants more resistant to flooding, research shows

Extreme weather phenomena are on the rise worldwide, including frequent droughts and fires. Floods are also a clear consequence of climate change.

13 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Researchers developed a weapon to combat drug-resistant malaria

As the efficiency of conventional antimalarial medications deteriorates, a novel approach to combating malaria that sees the disease turn against itself could provide a viable treatment for the hundreds of millions of people affected globally every year.

6 Jun 2022

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

The formation of aqueous droplets in macromolecules by liquid-liquid phase separation (or coacervation) is a popular topic in life sciences research. DNA is particularly interesting among the numerous macromolecules that form droplets because it is predictable and programmable, both of which are desirable properties in nanotechnology.

6 Jun 2022

Study identifies the regulatory function of non-coding 7S RNA

In human cells, a non-coding RNA molecule controls mitochondrial gene expression, according to new research published in the journal Cell. The research is the result of a collaboration between Sweden’s University of Gothenburg and Karolinska Institutet, as well as Germany’s University of Cologne.

3 Jun 2022

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Cas7-11, the first CRISPR enzyme that can make precise, directed cuts to strands of RNA without hurting cells, was identified and described last year by researchers at MIT’s McGovern Institute for Brain Research.

From Massachusetts Institute of Technology (MIT) 2 Jun 2022

Researchers discover distinctive antibacterial therapy that uses visible light-activated synthetic molecular machine

Infectious-bacteria-killing molecular machines have been persuaded to reconsider their goal.

2 Jun 2022

Researchers determine intracellular antibodies to cure diseases

Mermaid Bio GmbH of Munich, Germany, and WEHI of Melbourne, Australia, recently announced cooperation to identify and develop a unique class of therapeutic candidates that modify misbehaving proteins inside cells that can cause a variety of diseases.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 1 Jun 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers develop a new biochemical process to analyze plant immunity

Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.

From The Max Planck Institute 27 May 2022

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

A stomach adult stem cell population can fulfill two distinct functions: either help with digestion under normal conditions or take the lead on injury response. S

26 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022