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Study unravels the DNA repair mechanism by enzymes

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Study reveals how autoimmune antibodies can predict severe cases of COVID-19

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

From New York University (NYU) 9 Sep 2021

New technology harnesses a natural feature of therapeutic antibodies to attack blood cancer cells

Researchers at the University of Southampton and biopharma company UCB have found a way to enhance the natural ability of therapeutic antibodies to attack blood cancer cells using part of the human immune system known as the complement cascade, opening the way for a potential new class of treatments.

8 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Study provides deep insights into the association between genes and diseases

Scientists examined genomic data from more than 30,000 individuals and unraveled thousands of new regulatory regions that regulate disease-linked genes.

7 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Research shows how dendrimers avoid detection by the immune system

Tiny synthetic particles known as dendrimers have been shown to avoid detection by our immune system and so could be used to develop a new system to deliver drugs into the body without triggering a reaction.

3 Sep 2021

Study: Fat tissue of older mice lose the ability to restore body heat in cold temperatures

The evolution of humans has given them a level of protection from the risk of cold temperature with the ability to generate heat from fat stored in the body.

3 Sep 2021

Study reveals possibilities to disrupt dynamics and halt SARS-CoV-2 transmission

Researchers have simulated the transition of the SARS-CoV-2 spike protein structure from the time it recognizes the host cell to its entry into the cell.

2 Sep 2021

New approach to enhance cell-free biosynthesis with engineered yeast extracts

Think of cells as tiny factories: within their walls they have both the machinery to make products such as proteins, and the mechanisms for maintenance to keep processes running smoothly.

31 Aug 2021

Researchers fabricate 3D-integrated nanopores to detect single DNA molecules

Detecting DNA from a single cell is vital for the identification of genetic disorders and diseases.

From Osaka University 31 Aug 2021

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

From UC San Diego 20 Aug 2021

New method can efficiently convert plant matter into high-value bioproducts

A team of scientists at the University of Illinois Urbana-Champaign developed a bioprocess using engineered yeast that completely and efficiently converted plant matter consisting of acetate and xylose into high-value bioproducts.

18 Aug 2021

Study assesses the effectiveness of T-cell immune response to different SARS-CoV-2 variants

New mutations of the SARS-CoV-2 virus have been emerging continuously, enabling a more potent spread of the virus and allowing it to evade antibodies.

16 Aug 2021

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

The single-stranded genetic material RNA is best known for guiding the assembly of proteins in our cells and carrying the genetic code for viruses like SARS-CoV-2 and HIV.

16 Aug 2021

New molecule can effectively deplete cancer-protecting cells inside tumors

A new study has discovered a two-arm molecule that can effectively deplete cancer-protecting cells within tumors.

16 Aug 2021

Study shows plants reuse secondary metabolites in primary metabolism

Plant researchers identified that plants are capable of reusing specialized metabolic products and break them down to recover nutrients.

12 Aug 2021

Dileucine turns up muscle-building process more than leucine, study finds

In a randomized control study of 10 healthy young men, researchers compared how consuming the single amino acid leucine or its two-molecule equivalent, dileucine, influenced muscle-building and breakdown.

10 Aug 2021

Scientists show how lab-grown beating heart cells are vulnerable to SARS-CoV-2 infection

Cambridge scientists have grown beating heart cells in the lab and shown how they are vulnerable to SARS-CoV-2 infection. In a study published in Communications Biology, they used this system to show that an experimental peptide drug called DX600 can prevent the virus entering the heart cells.

6 Aug 2021

Experimental small molecule could help treat Parkinson’s disease in future

A new study has demonstrated the removal of damaged mitochondria from the brain cells of mice treated with a small molecule compound for Parkinson’s disease.

5 Aug 2021

Molecule News and Research

Study unravels the DNA repair mechanism by enzymes

Study reveals how autoimmune antibodies can predict severe cases of COVID-19

New technology harnesses a natural feature of therapeutic antibodies to attack blood cancer cells

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

Study provides deep insights into the association between genes and diseases

Miniature CRISPR-Cas system expands applicability and implications further

Research shows how dendrimers avoid detection by the immune system

Study: Fat tissue of older mice lose the ability to restore body heat in cold temperatures

Study reveals possibilities to disrupt dynamics and halt SARS-CoV-2 transmission

New approach to enhance cell-free biosynthesis with engineered yeast extracts

Researchers fabricate 3D-integrated nanopores to detect single DNA molecules

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

New method can efficiently convert plant matter into high-value bioproducts

Study assesses the effectiveness of T-cell immune response to different SARS-CoV-2 variants

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

New molecule can effectively deplete cancer-protecting cells inside tumors

Study shows plants reuse secondary metabolites in primary metabolism

Dileucine turns up muscle-building process more than leucine, study finds

Scientists show how lab-grown beating heart cells are vulnerable to SARS-CoV-2 infection

Experimental small molecule could help treat Parkinson’s disease in future

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